Protein Alignment ninaC and myo-6

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: NP_001022590.1
• Gene: myo-6 / 176764
• WormBaseID: WBGene00009730
• Length: 1235
• Species: Caenorhabditis elegans
• Alignment Length: 921
• Identity: 213/921 - (23%)
• Similarity: 412/921 - (44%)
• Gaps: 152/921 - (16%)

  Fly   335 EDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQP 399
            ||::.|....:.:::.:||.|......|::.|...:.:|..::...:.....:.|..|.|:|..|
 Worm    88 EDMSNLTFLNEASVLHNLRQRYYSMMIYTYSGLFCVFINPYKMLPIYTDSVASMYVNKRRAEMPP 152

  Fly   400 HIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRGATGRVESSIK--- 461
            |:|:|:|.|:::|:..||.|.::::|||.:||:.|.:.:|.:...:|.||:..  :.|||::
 Worm   153 HLFAVSDEAFRNMMSDKENQSMLITGESGAGKTENTKKVIAYFAMIGSGNKDQ--KSESSLENQV 215

  Fly   462 -----AILMLVNAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATTDGTQHNFHI 521
                 ||....|..|..|.:|:|......:.|.:.||:.|.....|:|||.||......:.::||
 Worm   216 VQANPAIEAFGNGATTRNYNSSRYGKFIRIHFDRKGKLVGGDIEHYLLEKSRVIKQAPGERSYHI 280

  Fly   522 FYYFYDFINQQNQLKE-YNLKAD-RNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREFENILRDI 584
            ||.    |..|..|:| |.|..: |:|:::.......|..         .:.|.::..:.....:
 Worm   281 FYQ----IMTQKALRERYGLSDNIRDYKFVSQAEITVPGM---------NDTEEWQITDGAFNVM 332

  Fly   585 DFNHKQLETVRKVLAAILNIGNIRFRQNGKYAEVENTDIVSRIA--ELLRVDEKKFMWSLTNFIM 647
            .|:.::.:.:.|:.:||::|||..|:|..:..:.|..|:.|..|  :|..::..:|:.:||...:
 Worm   333 GFSEREKDDLYKLCSAIMHIGNSTFKQKPRDEQAEVDDMTSPTAACKLFGINTDQFLNALTRPRI 397

  Fly   648 VKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIH----DM 708
            ..|.....:....::...|..|::..:|:|:.:::|.|:|..:.      .:::.::.:    |:
 Worm   398 KVGMEWVNKGQNVQQVDWAVGALSKAIYARMFNWLIKRVNKTLQ------ANSDEMVYYIGVLDI 456

  Fly   709 FGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKP 773
            .|||.|:||..|||.||.:||::|..:|..:|:.|..|.:.|.|:...::|..:..:...|:.||
 Worm   457 AGFEIFDRNSFEQLWINFVNEKLQQFFNHHMFVLEQEEYQREGIEWTFIDFGLDLQSCIELIEKP 521

  Fly   774 DGLFYIIDDASRSCQDQDLIMDRVSE-------------KHSQFVK------KHTATEISVAHYT 819
            .|:.        |..|::.|:.:.|:             ||..|.|      |......|:.||.
 Worm   522 LGIV--------SMLDEECIVPKASDMTYVDKLLTQHLGKHPNFQKAKPPKGKQAEAHFSIMHYA 578

  Fly   820 GRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNLTMPFEAVQHKDESERKS 884
            |.:.|:...:.|.|:|.:....:...::|..|.::.....:          ::....::|||::.
 Worm   579 GTVRYNAEQWLDKNKDPLNDSAVAILKTSDKEGVLYQLWEE----------YQTDVDREESEKRG 633

  Fly   885 YALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCIRADLEYKPRSFHSDVV 949
            .|    .|....:..:..|::..:|.:..:|:.||.   ....||:|||..:.:.......:.:|
 Worm   634 KA----QAKKKGKSASFLTVSTMYRESLTSLMTMLH---TTHPHFIRCIIPNEKKTSGLIDAPLV 691

  Fly   950 QQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFD--FDEPV---------EMTKDNCRLL 1003
            ..|:...|||:.:...:|||.:|:.|.:|..||..||.|  .|:..         :::|:|
 Worm   692 LNQLTCNGVLEGIRICRKGFPNRMMFADFRFRYAILAADEASDKDAAKASKAMLRKLSKNN---- 752

  Fly  1004 FLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKK----VIKVQSMMRALLARKRVKGGKVFKL 1064
              :|.::.:.:|.||||.|   ...||||.||:.:.    ::|.|..:|..||:...|.    :|
 Worm   753 --QLNVDTFKVGTTKVFFR---AGMLARLEELRDEALSAVILKFQCSLRHYLAQLEYKR----RL 808

  Fly  1065 GKKGPE---HHDVAA-------------SKIQKAFRGFRDRVRLPPLVNEKSGQLNEN------- 1106
            .::...   ..::.|             |:::...:|.:....:..| .:|..:|.||
 Worm   809 DREDAYPIIQENIRAWIKLRSWPWYRLFSRLKPMLKGMKSNAEIEAL-EKKCKELEENHKREEEA 872

  Fly  1107 ---TADFIRPFAKKWREKSIFQVLLHYRAARFQDFVNL---SQQVHIYNQRMVA----GLNKCTR 1161
               .||.:|....::.|.         :||..:|.:.|   ::::...|:.:.|    ......:
 Worm   873 RKKYADELRAKIDQYEET---------KAAHERDRMLLDKRNKEIEELNRNLKAESESNYENAKK 928

  Fly  1162 AVPFERINMRE 1172
            |...||:..:|
 Worm   929 ASELERLREKE 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	174/721 (24%)
myo-6	NP_001022590.1	Myosin_N	32..>67	CDD:460670
		MYSc_class_II	99..769	CDD:276951	174/721 (24%)
		Myosin_tail_1	855..>1206	CDD:460256	19/95 (20%)