Protein Alignment ninaC and Myo9a

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_063120884.1
• Gene: Myo9a / 171296
• RGDID: 621395
• Length: 2627
• Species: Rattus norvegicus
• Alignment Length: 1012
• Identity: 245/1012 - (24%)
• Similarity: 437/1012 - (43%)
• Gaps: 228/1012 - (22%)

  Fly   311 KEPELFVDRGYVKRFDEKPEKMYPEDLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSN 375
            :|....::||::    .:|::...:||.:|.:..::.::|:||:|....:.|:::|.||:::|..
  Rat   129 EERRRMMERGFL----PQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILIAINPF 189

  Fly   376 EIKQEFPQEFHAKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIK 440
            :....:..::...|......:.:|||::|||:||..||..|:.|.||:||||.|||:.:...||.
  Rat   190 KFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSGKTQSTNFLIH 254

  Fly   441 HLCYLGDGNRGATGRVESSI----KAILMLVNAGTPVNNDSTRCVLQYCLTFGK--------TGK 493
            ||..|  ..:|....||..|    ..:....||.|..||:|:|        |||        ||.
  Rat   255 HLTAL--SQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSR--------FGKFIQVNYQETGT 309

  Fly   494 MSGAVFNMYMLEKLRVATTDGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPS 558
            :.||....|:|||.|:...:..:.|:|:|||.....:::.:| .::||....|.:|.   ::...
  Rat   310 VLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEEERL-AFHLKQPEEYHFLN---QITKK 370

  Fly   559 KLKYRRDD-----------PEGNVERYREFENI---LRDIDFNHKQLETVRKVLAAILNIGNIRF 609
            .|:...||           .||...|: :||.:   :..:.|..|....:..:|:|||::|||.:
  Rat   371 PLRQSWDDYCYDSEPDCFTVEGEDLRH-DFERLQLAMEMVGFLPKTRRQIFSLLSAILHLGNISY 434

  Fly   610 RQ---NGKYAEVENTDIVSRIAELLRVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVA 671
            ::   .....::.|.:::..::|||.|.|:....:|.....|..|......|...||...|:::|
  Rat   435 KKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLILPYKLAEAVTVRNSMA 499

  Fly   672 STLYSRLVDFIINRINMNMSFPRAVFGDTNAIIIH--DMFGFECFNRNGLEQLMINTLNEQMQYH 734
            .:|||.|.|:|:.|||..:...:.:..||..:.|.  |:||||.:..|..||..||..||::|::
  Rat   500 KSLYSALFDWIVFRINHALLNSKDLEKDTKTLSIGVLDIFGFEDYENNSFEQFCINFANERLQHY 564

  Fly   735 YNQRIFISEMLEMEAEDIDTINLNFYDNKTALDNLLTKPDGLFYIIDDASRSCQ-DQDLIMDRVS 798
            :||.||..|..|...|.|...|:::.||...::.:..||.||.:::|:.|...| ....::|:..
  Rat   565 FNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKPTGLLHLLDEESNFPQATNQTLLDKFK 629

  Fly   799 EKHSQ--FVKKHTATE--ISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDE-------- 851
            .:|.:  :::.....|  ..:.||.|::.|..:.|.:.|.|.:.|:::...|||.:.
  Rat   630 HQHEENSYIEFPAVMEPAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSRNAFVSGMTGI 694

  Fly   852 --------SIMLMFTNQLT------------KAG-NLTMP---------FEAVQH---------- 876
                    :::..|...:.            |:| :.|.|         |..:||
  Rat   695 DPVAVFRWAVLRAFFRAVVAFREAGKRHIQRKSGHDDTTPCTILKSMDSFSFLQHPVHQRSLEIL 759

  Fly   877 ---KDES---ERKS--------YALNTL------------------------------------- 890
               |:|.   .||:        ..:|||
  Rat   760 QRCKEEKYSITRKNPRTPLSDLQGMNTLNEKNQHDTFDIAWNVRTGIRQSRLPTNNTSLLDKDGI 824

  Fly   891 -----SAGCISQVNNLRTLAANFR-----------------FTCLTLLKMLSQNANLGVH----- 928
                 |:..:.:.:.:.|...|||                 .|.|||...::::. |.:|
  Rat   825 FANSASSKLLERAHGILTRNKNFRSKPVLPKHLLEVNSLKHLTRLTLQDRITKSL-LHLHKKKKP 888

  Fly   929 ------------------------FVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGF 969
                                    ||:|||::.|..|..|...:|.:|::..|:|:||..||.|:
  Rat   889 PSISAQFQVSLSKLMETLDQAEPYFVKCIRSNAEKLPLRFSDALVLRQLRYTGMLETVRIRQSGY 953

  Fly   970 SSRLPFDEFLRRYQFLAFDFDEPVEMTKDNCRLLFLRLKM--EGWALGKTKVFLRYYNDEFLARL 1032
            ||:..|.:|:..:..|   ..:.:..:|.|.:..|.::.:  :.:.:|||.|||:.:..:.|..|
  Rat   954 SSKYSFQDFVSHFHVL---LPQHIIPSKFNIQDFFRKININPDNYQVGKTMVFLKEHERQHLQDL 1015

  Fly  1033 YELQV-KKVIKVQSMMRALLARKRVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLV 1096
            ...:| :::|.:|...|.||:|::..             |...|:..||:.:|.:.::.::....
  Rat  1016 LHQEVLRRIILLQRWFRVLLSRQQFL-------------HLRQASVIIQRFWRNYLNQKQVRNAA 1067

  Fly  1097 NEKSGQLNENTADFIRPFAKKWREKSIFQVLLHYRAA 1133
            .||...:..:.|..::   ..||.....|..|..|||
  Rat  1068 VEKDAFIMASAASLLQ---ASWRAHLERQRYLELRAA 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	213/863 (25%)
Myo9a	XP_063120884.1	None