Protein Alignment ninaC and Myo95E

DIOPT Version :10

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_061502440.1
• Gene: Myo95E / 1274548
• VectorBaseID: AGAMI1_000001
• Length: 1256
• Species: Anopheles gambiae
• Alignment Length: 1256
• Identity: 255/1256 - (20%)
• Similarity: 430/1256 - (34%)
• Gaps: 436/1256 - (34%)

  Fly   336 DLAALENPVDENIIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFHAKYRFKSRSENQPH 400
            |...|||..:|:.|.:|..|......|::||..|::||..:..|.:..:...||..||..:..||
Mosquito    23 DSVLLENLSEESFINNLHQRYKRDLIYTYIGTFLVALNPYKPLQIYNPDQVRKYATKSLFQLPPH 87

  Fly   401 IFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRG-------------- 451
            ||::|:.|:|.:|::.|.|.|:::||..|||:.::.:::..|..|.:..|.
Mosquito    88 IFALANSAHQFLLNYNEDQCIIMAGECGSGKTESSHMIVHFLTQLSEMRRSRAPIFSLRGSNPNS 152

  Fly   452 ----------------------ATGRVES---------------------------SIKAILMLV 467
                                  :.||::|                           |.:.:..:|
Mosquito   153 RQSTPKHSTISRVGSSFESAAPSGGRLDSIMKYNSSRQQKCSHEKTVEFDLISHHKSTENLPAMV 217

  Fly   468 NAG-TPV---------------------------------------------------------- 473
            |.| .||
Mosquito   218 NYGFMPVATMPKCLKHSNQSISRSTEGNEFPTKSTLKSATTMGSCPKHNCTSSHAELNRMCGGAS 282

  Fly   474 ------------------NNDSTRCV----LQYCLT----------------------------- 487
                              :|:|||.:    ....||
Mosquito   283 PSPSLQKRSNLMRCCHQNSNNSTRSIHKSSSSIALTHDHGTTSPSTFHRRQILKSISKEVYIRDL 347

  Fly   488 --------------------------------FGK--------TGKMSGAVFNMYMLEKLRVATT 512
                                            |||        .|...|....:|||||.||.|.
Mosquito   348 ELQKMRERVAQAEIFLEAMGNAVTVKNINSSRFGKFFDIEFDYKGDPVGGHLTLYMLEKSRVTTR 412

  Fly   513 DGTQHNFHIFYYFYDFINQQNQLKEYNLKADRN---YRYLRVPPEVPPSKLKYRRDDPEGNVERY 574
            ...:.||||||......:.| .||  :||..||   |..|         |..:..:|...|   :
Mosquito   413 ASGERNFHIFYQLLSGADIQ-LLK--SLKLQRNIDKYELL---------KNTFANEDDRTN---F 462

  Fly   575 REFENILRDIDFNHKQLETVRKVLAAILNIGNIRF-----RQNGKYAEVENTDIVSRIAELLRVD 634
            ...:..|..:.|...::.::..:||.:|.:||:.|     ....:..|:.|...:..||:||::|
Mosquito   463 TFTKRSLEILGFGQDEIFSIFTILAVVLKLGNLTFIPTTNIDGSEGCEISNEYELDEIAQLLQLD 527

  Fly   635 EKKFMWSLTNF-----------IMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRIN- 687
            .:.....||..           ..:....|.|.::|          :..|||.||..:|::|:|
Mosquito   528 NQMLFNCLTRLGDNWAQLEPDGTEIDASYASRIKFT----------LCRTLYGRLFTWIVSRVND 582

  Fly   688 -MNMSFPRAVFGDTNAIIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEA-- 749
             :.:.....|......|.:.|.:|||...:|..:|..||..||::|.|     ||..:|:.:.
Mosquito   583 ALKLKTSGTVGSRGKTIGLLDFYGFEALEKNTFDQFAINYCNERLQQH-----FIKSVLKHQQDL 642

  Fly   750 ---EDIDTINLNFYDNKTALDNLLTKP-DGLFYIIDDASRSCQDQDLIMDRVSE---KHSQFVKK 807
               |.:|.|.::|:|| ..:..|:.|| .|:.:::|:.  ...:..|::.|:.:   .|:.|:.:
Mosquito   643 YVNEGLDWIRIDFFDN-APICELIDKPCFGILHLLDEP--QVVNDGLLLTRLHQCCAGHTNFLAR 704

  Fly   808 HTATE---ISVAHYTGRIIYDTRAFTDINRDFVPPEMIE-TFRSSLDESIMLMFTNQLTKAGNLT 868
            ..:..   ..|.|:.|.::|.|..|.:.|.|.:|..:.. .|:|.      |:..:.|...||
Mosquito   705 DASLPSNCFQVRHFEGPVVYTTNGFIEKNLDLLPRHISSCLFQSD------LLIASCLFPEGN-- 761

  Fly   869 MPFEAVQHKDESERKSYALNTLSAGCISQVNNLRTLAANFRFTCLTLLKMLSQNANLGVHFVRCI 933
                   .|..|.||..:|:          |||||       :..||||:|.|.:|   |::.||
Mosquito   762 -------PKRHSNRKPSSLS----------NNLRT-------SLQTLLKLLEQRSN---HYIFCI 799

  Fly   934 RADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLA-FDFDEPVEMTK 997
            :.:...:.:.|...:||.|::.|.::..:...:.|....:....||.||:.|. :.:........
Mosquito   800 KPNELKQAKMFELGLVQHQVRYLCLMPLINLWRNGHCFNMVHSRFLARYKLLCQYTWPHFTGTIV 864

  Fly   998 DNCRLLFLRLKMEG--WALGKTKVFLR-----YYNDEF-LARLYELQVKKVIKVQSMMRALLARK 1054
            |...|:...:.:.|  :.:|:.|||:|     |..||| ..||.||    .|.:|...|....||
Mosquito   865 DGVALIIRSVPLPGAEFTIGRKKVFIRSPRTVYELDEFRKVRLNEL----AILIQKTYRCYTKRK 925

  Fly  1055 RVKGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDR------------------------------ 1089
            |....:          |..:.   |...:|.:|:|
Mosquito   926 RFLTLR----------HSQLI---IASYWRTWREREKIRLVEFRKQALWAVQVIGRFFVLLKTRE 977

  Fly  1090 ------VRLP-----PLVNE--KSGQLNENTADFIRPFAKKW-----------------REKSIF 1124
                  :|||     |:.:|  .:......|:..:|....:|                 |||...
Mosquito   978 FLLTLLLRLPHDNMSPICHEWPSAPTFLAETSQLLRTIFHRWRCYKYRKSFDQPARNRMREKVTA 1042

  Fly  1125 QVLLHYRAARFQ---------DFVNLSQQVH------IYNQRMVAG---LNKCTRAVPFERINMR 1171
            .::...|...:.         |::.|.|.:.      .:|.:.|..   :||..|
Mosquito  1043 SIIFKDRKVSYPRSVAHPFHGDYIRLRQNIQWKRVSCEHNDQYVVFADIINKIAR---------- 1097

  Fly  1172 EVNSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQA---FPNQLLTQHMEDDEPWDSP 1233
              :|.:..|:.:.|......|........:|.: ||:.|.|.:   :.:.:...|:..|....|.
Mosquito  1098 --SSGKFIPILLVISTNSMLLLDQKTMQIKYRI-PASEIYRMSLSPYFDDIAVIHIRADNYCSSN 1159

  Fly  1234 L-QRNPSMTSCALTYNAYKKE 1253
            : .|:.|.|.|.......||:
Mosquito  1160 MSDRSESPTGCLFQSEIGKKK 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785
		MYSc_Myo21	346..1022	CDD:276848	193/925 (21%)
Myo95E	XP_061502440.1	None