Protein Alignment ninaC and myo3a

DIOPT Version :9

• Sequence 1: NP_523503.2
• Gene: ninaC / 34012
• FlyBaseID: FBgn0002938
• Length: 1501
• Species: Drosophila melanogaster
• Sequence 2: XP_031760347.1
• Gene: myo3a / 100495574
• XenbaseID: XB-GENE-6032645
• Length: 1607
• Species: Xenopus tropicalis
• Alignment Length: 1568
• Identity: 463/1568 - (29%)
• Similarity: 746/1568 - (47%)
• Gaps: 241/1568 - (15%)

  Fly    10 PDPTDKFEIYEEIAQGVNAKVFRAKELDNDRIVALKI-----QHYDEEHQVSIEEEYRTLRDYCD 69
            |||||.::|.|.|.:|...|||:.....|....|:||     :..|||    ||.||..|:...|
 Frog    15 PDPTDTWDICETIGKGTYGKVFKVTNKKNGSKAAVKILDPFHEDIDEE----IEAEYNILKALSD 75

  Fly    70 HPNLPEFYGVYKLSKPNGPDEIWFVMEYCAGGTAVDMVNKLLKLDRRMREEHIAYIIRETCRAAI 134
            |||:.:|||:|........|::|.|:|.|.||:..::...|||...||.|..||||:.|.....:
 Frog    76 HPNVVKFYGMYFKKDVKTGDQLWLVLELCNGGSVTELAKGLLKRGERMSEPIIAYILHEAMMGLL 140

  Fly   135 ELNRNHVLHRDIRGDNILLTKNGRVKLCDFGLSRQVDSTLGKRGTCIGSPCWMAPEVVSAMESRE 199
            .|:::..:|||::|:|||||..|.|||.|||:|.|:.:|...|.|.:|:|.||||||::..:..:
 Frog   141 YLHQHKTIHRDVKGNNILLTTVGGVKLVDFGVSAQLTNTRLHRNTSVGTPFWMAPEVIACEQQVD 205

  Fly   200 PDITVRADVWALGITTIELADGKPPFADMHPTRAMFQIIRNPPPTLMRPTNWSQQINDFISESLE 264
            .....|.|||:||||.|||.||.||.||:||.||:|:|.|||||||.:|..||.:.||||::.|.
 Frog   206 TTYDARCDVWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPTLRQPELWSAEFNDFINKCLI 270

  Fly   265 KNAENRPMMVEMVEHPFLTELIENEDEMRSDIAEMLELSRDVKTLYKE--PELFVDRGYVKRFDE 327
            |:.|.||.:.:::||||:.:|.:||:.::..:.|::::.:.:..:.|:  ..:...:|:.|
 Frog   271 KDFEKRPTVSDLLEHPFIKQLKDNENALQKQLMELIDIHQQMGIMAKKRHERINTKKGHFK---- 331

  Fly   328 KPEKMYP-----EDLAALENPVDEN-IIESLRHRILMGESYSFIGDILLSLNSNEIKQEFPQEFH 386
              |.|.|     :|||.|| .:||| :.:.|:.|....:.|:::||||:::|.......:..::.
 Frog   332 --ESMAPNQDDVDDLATLE-ALDENTVTDQLQKRYNRDQIYTYVGDILVAVNPFRPMDLYSSQYS 393

  Fly   387 AKYRFKSRSENQPHIFSVADIAYQDMLHHKEPQHIVLSGESYSGKSTNARLLIKHLCYLGDGNRG 451
            ..|....|::|.||||:|||:|||.|:.:...|.||:||||.:||:..|.||::.|..||..|..
 Frog   394 QMYIGAKRTDNPPHIFAVADLAYQSMVTYNSDQCIVISGESGAGKTEGAHLLVQQLTVLGKANNR 458

  Fly   452 ATGRVESSIKAILMLV----NAGTPVNNDSTRCVLQYCLTFGKTGKMSGAVFNMYMLEKLRVATT 512
            .   ::..|..:..||    ||.|.:|.:|:|......:.|...|.:..|..:.|:|||.||...
 Frog   459 T---LQEKILQVNNLVEAFGNACTIINENSSRFGKYLEMKFTSNGTVVAAQISEYLLEKSRVVHQ 520

  Fly   513 DGTQHNFHIFYYFYDFINQQNQLKEYNLKADRNYRYLRVPPEVPPSKLKYRRDDPEGNVERYREF 577
            ...:.|||||||.|..::::.:|..|.|            |::.|.  :|.:::   :::..::|
 Frog   521 ALGEKNFHIFYYIYAGLSEKKKLAHYKL------------PDIKPP--RYLQNE---HIKMVQDF 568

  Fly   578 -------------ENILRDIDFNHKQLETVRKVLAAILNIGNIRF------RQNGKYAEVENTDI 623
                         |...:.|.|:.::|.:|..:||||||:|||.|      .|..| :.:.|..:
 Frog   569 MNKPFYKSQFELIEQCFKVIGFSMEELGSVYSILAAILNVGNIDFTSVASEHQIDK-SHINNPTV 632

  Fly   624 VSRIAELLRVDEKKFMWSLTNFIMVKGGIAERRQYTTEEARDARDAVASTLYSRLVDFIINRINM 688
            :...|.||.:...:...:||:..:|..|....:|.|.|:|.|.|||::..||.||..:|:||||.
 Frog   633 LENAASLLCIQPDELKDALTSHCVVTRGETIIQQNTVEKAADVRDAMSKALYGRLFSWIVNRINA 697

  Fly   689 NMSFPRAVFGDTNA--IIIHDMFGFECFNRNGLEQLMINTLNEQMQYHYNQRIFISEMLEMEAED 751
            .:. |..:..|...  |.|.|:||||.|.:|..|||.||..|||:|:::||.||..|..|...||
 Frog   698 LLK-PEKLSEDDAGFNIGILDIFGFENFKKNSFEQLCINIANEQIQFYFNQHIFAWEQNEYLNED 761

  Fly   752 IDTINLNFYDNKTALDNLLTKPDGLFYIIDDASR--SCQDQDLIMDRVSEKHSQFVK-------K 807
            :|...:.:.||:..||..|.||.||..::|:.||  ...||.|:     ||....:|       |
 Frog   762 VDVRLIEYEDNRPILDMFLQKPMGLLSLLDEESRFPRATDQTLV-----EKFEDNLKSKNFWRPK 821

  Fly   808 HTATEISVAHYTGRIIYDTRAFTDINRDFVPPEMIETFRSSLDESIMLMFTNQLTKAGNL----T 868
            .......:.||.|:::|:...|.:.|||.:|.:::...|||.:..|.::.:|.|||.|||    |
 Frog   822 RVDLTFGIHHYAGKLLYNASGFLEKNRDTLPADIVLLLRSSENSLIRILASNPLTKTGNLAHTKT 886

  Fly   869 MPFEAVQ----HKDESERKSYALNTLSAGCISQVNNLR--TLAANFRFTCLTLL-KMLSQNANLG 926
            ....::|    ||..:..||....|...   .:..|::  |:::.||::.:.|| ||::...
 Frog   887 KGGTSLQSWTSHKSSNHSKSDFSETYHP---RETTNMKTQTVSSYFRYSLMDLLSKMVAGQP--- 945

  Fly   927 VHFVRCIRADLEYKPRSFHSDVVQQQMKALGVLDTVIARQKGFSSRLPFDEFLRRYQFLAFDFDE 991
             ||||||:.:.:.....|..:.|..|::..|:|:|...|:.|:|.|:.|..|::||:.|.|..:|
 Frog   946 -HFVRCIKPNNDRLANKFDREKVLVQLRYTGILETARIRRLGYSHRILFANFIKRYRLLCFKSNE 1009

  Fly   992 PVEMTKDNCRLLFLRLKMEGWALGKTKVFLRYYNDEFLARLYELQVKKVIKVQSMMRALLARKRV 1056
            ...::.::|..:..:..::.|.||||||||:||:.|.|.|:.:..|..::.||:.:|..||.||.
 Frog  1010 DPPVSPESCAAILEKANVDNWVLGKTKVFLKYYHAEHLDRMIKHIVGGIVLVQACVRGWLAAKRF 1074

  Fly  1057 KGGKVFKLGKKGPEHHDVAASKIQKAFRGFRDRVRLPPLVNEKSGQLNENTADFIRPFA------ 1115
            :  ||.       ...:.:|.|||.|:||:..|..:..:.:||   :.|:.....:.:|
 Frog  1075 Q--KVL-------ARREESAVKIQSAYRGYVVRKEMGHIQSEK---MMEHIITQFQAYARGYLVR 1127

  Fly  1116 KKWREK----SIFQVLLHYRAARFQDFV----------------NLSQQVHIYNQRMVAGLNKCT 1160
            |:.:|:    :...:..|||..:.:...                |:..:.:...:.:..|.::..
 Frog  1128 KRIKEQHENDAAITIQSHYRGFKERKSFKRKRESMKSKQCKTPENVEPEQNSEEEIIAEGKSEEE 1192

  Fly  1161 RAVPF----ERINMREVNSSQLGPLPVPIKKMPFRLDQIPFYDTQYMVDPANSISRQAFPNQLLT 1221
            .||..    ||..|.|.:.|. |.:..|                    :..:::.....||.
 Frog  1193 AAVVIQSHKERKEMNEPHQSN-GAVTAP--------------------EAEDTVDLDTGPNN--- 1233

  Fly  1222 QHMEDDEPWDSPLQRNPSMTSCALTYNAYKKEQACQTNWDRMGESDNIYNQGYFRDPQQLRRNQM 1286
               .||...||  :.:.:.|.....|..::..:..:   :|.|...|         |.:...|..
 Frog  1234 ---NDDTEKDS--REDQAATVIQSNYRGHRDRKKLK---ERSGHEIN---------PTKTDSNNP 1281

  Fly  1287 QMNMNAYNNAYNSYNSNYNNQNWGVHRSGSRRNSLKGYAAPPPPPPPMPSSNYYRNNPNQQQRNY 1351
            ...:...|....|.|.....    :..:|.:..........|.|...:||        ||:....
 Frog  1282 TEELIQANGIQGSNNPTEEL----IQANGIQEGQQATNGKSPEPETTLPS--------NQEDVVK 1334

  Fly  1352 QQRSSYPPSDPVRELQNMARNEGDNSEDPPFNFKAMLRKTNYPRGSETNTYDFNNRRGSDSGDQH 1416
            |......|::...|....:.:|.|..|:       :|..|:..:.:....   :|.||....|
 Frog  1335 QNEKVDSPAEDNEEEAVPSTSENDQHEE-------LLEDTDRDKAAVVIQ---SNYRGHKERD-- 1387

  Fly  1417 TFQPPKLRSTGR---RYQDDEGYNSSSGNYGVSRKFGQQQRAPTLRQSPASVGRSFEDSNARSFE 1478
                 |||..|:   :...||..|       :..|..:.:....|::                .|
 Frog  1388 -----KLRKEGKIPAKKGKDEKTN-------IKEKNSENETLSVLKE----------------IE 1424

  Fly  1479 EAGSYVEE 1486
            :..::.||
 Frog  1425 DLAAFTEE 1432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ninaC	NP_523503.2	STKc_myosinIII_N_like	9..282	CDD:270785	125/276 (45%)
		S_TKc	16..282	CDD:214567	120/270 (44%)
		MYSc	327..1034	CDD:214580	245/757 (32%)
		MYSc_Myo21	346..1022	CDD:276848	230/721 (32%)
myo3a	XP_031760347.1	PKc_like	7..288	CDD:419665	125/276 (45%)
		MYSc_Myo3	353..1040	CDD:276830	229/720 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49486
Inparanoid	1	1.050	629	1.000	Inparanoid score	I837
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D25137at33208
OrthoFinder	1	1.000	-	-		FOG0003766
OrthoInspector	1	1.000	-	-		otm47602
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2623
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060