Protein Alignment Wnt10 and WNT2B

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Alignment Length: 472
• Identity: 148/472 - (31%)
• Similarity: 206/472 - (43%)
• Gaps: 120/472 - (25%)

  Fly    12 EQQQLPQQQKQQQEAGSSSSSNSSSNNLVATPATSRHCNLHLIVMIILA-CCTRWLY-GLPDGRA 74
            |..|||.::........|.::...|.   |:......|.|.|:::.:.| ..|.|.| |....|.
Human     9 EAAQLPLRRASAPVPVPSPAAPDGSR---ASARLGLACLLLLLLLTLPARVDTSWWYIGALGARV 70

  Fly    75 TCRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHA--SSL 137
            .|.::|||...|.:||.:..|:..:..||....|||||.||:.|||||::|.    ..|.  ..:
Human    71 ICDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLD----RDHTVFGRV 131

  Fly   138 LKKGYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYL 202
            :.:..||:||.:|||:|||.|::.||||||.|..|.|||
Human   132 MLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDP-------------------------- 170

  Fly   203 ETNQILTPEEEKKYERSKIASR---WKWGGCSHNMDFGVEYSKLFLDCREK-AGDIQSKINLHNN 263
                         |.|.:...:   :.|||||.|:.:||.::|.|:|.:|| ..|.::.:|||||
Human   171 -------------YTRGRHHDQRGDFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNN 222

  Fly   264 HAGRIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVV 328
            ..||.||...::..|||||:||||.|:|||::..||.
Human   223 RCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFR---------------------------- 259

  Fly   329 VLKRARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAAR 393
                                               .|||...||:|. .|:....|..|:..|||
Human   260 -----------------------------------RTGDYLRRRYDG-AVQVMATQDGANFTAAR 288

  Fly   394 MA--RKLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAE 456
            ..  |...|.|.|:..||::|..|..|...||.||.|::.:..:|||..:|||||:......|..
Human   289 QGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVT 353

  Fly   457 RCHCKFQWCCNVECEEC 473
            :|.|||.|||.|.|:||
Human   354 QCECKFHWCCAVRCKEC 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	123/391 (31%)
WNT2B	NP_078613.1	wnt	74..380	CDD:306592	131/404 (32%)
		WNT-core domain	107..379		119/371 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740