Protein Alignment Wnt10 and WNT11

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_011543540.1
• Gene: WNT11 / 7481
• HGNCID: 12776
• Length: 364
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 125/451 - (27%)
• Similarity: 178/451 - (39%)
• Gaps: 125/451 - (27%)

  Fly    55 VMIILACCTRWLYGL--------PDGRAT-----CRSVPGLTKDQVELCYKASDVTAAALEGLDM 106
            ::..||..|...||:        |...|.     |:.:.||...||:||....::....:.....
Human    11 LLFALALQTGVCYGIKWLALSKTPSALALNQTQHCKQLEGLVSAQVQLCRSNLELMHTVVHAARE 75

  Fly   107 AIRECQIQFQWHRWNCSSLSTKSRN----PHASS---LLKKGYRESAFAFAISAAGVAHSVARAC 164
            .::.|:..|...||||||:......    ..||:   |...|.|||||.:|:|||.::|::||||
Human    76 VMKACRRAFADMRWNCSSIELAPNYLLDLERASADLPLPPSGTRESAFVYALSAAAISHAIARAC 140

  Fly   165 SQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYERSKIASRWKWGG 229
            :.|.|..|.|.|.........|                                       :|||
Human   141 TSGDLPGCSCGPVPGEPPGPGN---------------------------------------RWGG 166

  Fly   230 CSHNMDFGVEYSKLFLDCREKAGDIQSKIN----LHNNHAGRIAVSNNMEFRCKCHGMSGSCQLK 290
            |:.|:.:|:.....|.|...|.....|:.|    |||:..||.|:..::|.:|||||:||||.::
Human   167 CADNLSYGLLMGAKFSDAPMKVKKTGSQANKLMRLHNSEVGRQALRASLEMKCKCHGVSGSCSIR 231

  Fly   291 TCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARNKKSNGGSGSGSTSPDLDSTD 355
            ||||...:...|...||.::..|..|....:|..:.:|                   ..|||...
Human   232 TCWKGLQELQDVAADLKTRYLSATKVVHRPMGTRKHLV-------------------PKDLDIRP 277

  Fly   356 ASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAARMARKLETSLFYYQRSPNFCERDLGADI 420
            ..         |||                                |.|.|.||:||.::.....
Human   278 VK---------DSE--------------------------------LVYLQSSPDFCMKNEKVGS 301

  Fly   421 QGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQWCCNVECEECH--VEEWI 479
            .||..|:||:.:..||.|..:|||||::....|..||||||:.|||.|.|..|.  ||.::
Human   302 HGTQDRQCNKTSNGSDSCDLMCCGRGYNPYTDRVVERCHCKYHWCCYVTCRRCERTVERYV 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	109/394 (28%)
WNT11	XP_011543540.1	wnt	47..364	CDD:302926	117/415 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152247
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740