Protein Alignment Wnt10 and WNT6

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_006513.1
• Gene: WNT6 / 7475
• HGNCID: 12785
• Length: 365
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 141/442 - (31%)
• Similarity: 194/442 - (43%)
• Gaps: 101/442 - (22%)

  Fly    54 IVMIILACCTR-----WLYGLP---DGRATCRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRE 110
            :::::|.|...     |..|.|   |..:.||....|...|.|||....:|.|....|..:.:||
Human    11 LLLLLLLCPAHVGGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRE 75

  Fly   111 CQIQFQWHRWNCSSLSTKSRNPHASS---LLKKGYRESAFAFAISAAGVAHSVARACSQGRLMSC 172
            ||.||::.||||||        |:.:   :|::..||:||.|||:|||.:|:|.:|||.|.|:.|
Human    76 CQFQFRFRRWNCSS--------HSKAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQC 132

  Fly   173 GCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYERSKIASRWKWGGCSHNMDFG 237
            ||.....|.....:....                  ||.........:.::.|:||||..::|||
Human   133 GCQAPRGRAPPRPSGLPG------------------TPGPPGPAGSPEGSAAWEWGGCGDDVDFG 179

  Fly   238 VEYSKLFLDCREK--AGDIQSKINLHNNHAGRIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFH 300
            .|.|:||:|.|.|  .|||::.:.||||.|||:||.::....|||||:||||.|:|||:..|.|.
Human   180 DEKSRLFMDARHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFR 244

  Fly   301 IVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGT 365
            .||..|..:|..|..|    :|..:...:|...|..|..|
Human   245 EVGARLLERFHGASRV----MGTNDGKALLPAVRTLKPPG------------------------- 280

  Fly   366 GDSETRRHDELGVERGTRQPSADKNAARMARKLETSLFYYQRSPNFCERDLGADIQGTVGRKCNR 430
                                             ...|.|...||:||..:......||.||.||.
Human   281 ---------------------------------RADLLYAADSPDFCAPNRRTGSPGTRGRACNS 312

  Fly   431 NTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQWCCNVECEECHVEEWISIC 482
            :.....||..|||||||.|...:..|.|.|:|.|||.|:|..|.|.:.:|:|
Human   313 SAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLC 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	125/388 (32%)
WNT6	NP_006513.1	wnt	47..364	CDD:278536	132/404 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..164		3/41 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810