Protein Alignment Wnt10 and WNT4

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_011539899.1
• Gene: WNT4 / 54361
• HGNCID: 12783
• Length: 373
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 135/402 - (33%)
• Similarity: 195/402 - (48%)
• Gaps: 105/402 - (26%)

  Fly    75 TCRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASSLLK 139
            ||..:.||.:.||::|.:..:|..:...|..:||.|||.||:..|||||:|.:.   |....::.
Human    64 TCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSL---PVFGKVVT 125

  Fly   140 KGYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLET 204
            :|.||:||.:|||:||||.:|.||||.|.|..||||.|::.
Human   126 QGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHG------------------------ 166

  Fly   205 NQILTPEEEKKYERSKIASRWKWGGCSHNMDFGVEYSKLFLDCREK---AGDIQSKINLHNNHAG 266
               ::|:            .::|.|||.|:.:||.:|:.|:|.||:   |...::.:|||||.||
Human   167 ---VSPQ------------GFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAG 216

  Fly   267 RIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLK 331
            |.|:..:|...|||||:||||::||||::.|.|..||..||.:|..|..|:...:|:...:|
Human   217 RKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALV--- 278

  Fly   332 RARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAARMAR 396
             .||.:.                                             :|..|::
Human   279 -PRNAQF---------------------------------------------KPHTDED------ 291

  Fly   397 KLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCK 461
                 |.|.:.||:|||:|:.:.:.||.||.||:.:...|||..||||||........||||.||
Human   292 -----LVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCK 351

  Fly   462 FQWCCNVECEEC 473
            |.|||.|:|.:|
Human   352 FHWCCFVKCRQC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	127/386 (33%)
WNT4	XP_011539899.1	wnt	71..373	CDD:278536	132/395 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740