Protein Alignment Wnt10 and WNT16

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_476509.1
• Gene: WNT16 / 51384
• HGNCID: 16267
• Length: 365
• Species: Homo sapiens
• Alignment Length: 458
• Identity: 133/458 - (29%)
• Similarity: 196/458 - (42%)
• Gaps: 124/458 - (27%)

  Fly    46 SRHCNLHLIVMIILACCTR----WL----YGLPDGRATCRSVPGLTKDQVELCYKASDVTAAALE 102
            :|.|.|...::::.....:    ||    :|:|: :..|.::| |...|.|||.:...:..:..|
Human    10 ARLCALWAALLVLFPYGAQGNWMWLGIASFGVPE-KLGCANLP-LNSRQKELCKRKPYLLPSIRE 72

  Fly   103 GLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASS-----LLKKGYRESAFAFAISAAGVAHSVAR 162
            |..:.|:||..||:..||||...:..:..|..:|     .|..|.:|:||.:|:.|||:.|||.|
Human    73 GARLGIQECGSQFRHERWNCMITAAATTAPMGASPLFGYELSSGTKETAFIYAVMAAGLVHSVTR 137

  Fly   163 ACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYERSKIASRWKW 227
            :||.|.:..|.||.|:.                                     .....:..|.|
Human   138 SCSAGNMTECSCDTTLQ-------------------------------------NGGSASEGWHW 165

  Fly   228 GGCSHNMDFGVEYSKLFLD-----CREKAGDIQSKINLHNNHAGRIAVSNNMEFRCKCHGMSGSC 287
            ||||.::.:|:.:|:.|||     ...|...:...:|||||.|||.||:..|...|:|||:||||
Human   166 GGCSDDVQYGMWFSRKFLDFPIGNTTGKENKVLLAMNLHNNEAGRQAVAKLMSVDCRCHGVSGSC 230

  Fly   288 QLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARNKKSNGGSGSGSTSPDLD 352
            .:|||||:...|..:|.:||.::..:|.:.                                  |
Human   231 AVKTCWKTMSSFEKIGHLLKDKYENSIQIS----------------------------------D 261

  Fly   353 STDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAARMARKL---ETSLFYYQRSPNFCER 414
            .|                        :|..|:...|:      ||:   :..|.|..:|||:|..
Human   262 KT------------------------KRKMRRREKDQ------RKIPIHKDDLLYVNKSPNYCVE 296

  Fly   415 DLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQWCCNVECEECHVEEWI 479
            |....|.||.||:|||.:..:|||..||||||::..:.|..|||.|||.|||.|.|..|.....:
Human   297 DKKLGIPGTQGRECNRTSEGADGCNLLCCGRGYNTHVVRHVERCECKFIWCCYVRCRRCESMTDV 361

  Fly   480 SIC 482
            ..|
Human   362 HTC 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	118/396 (30%)
WNT16	NP_476509.1	wnt	52..365	CDD:306592	124/414 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810