Protein Alignment Wnt10 and Wnt10b

DIOPT Version :9

• Sequence 1: NP_609109.3
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_035848.1
• Gene: Wnt10b / 22410
• MGIID: 108061
• Length: 389
• Species: Mus musculus
• Alignment Length: 455
• Identity: 176/455 - (38%)
• Similarity: 244/455 - (53%)
• Gaps: 91/455 - (20%)

  Fly    46 SRHCNLHLIVMIILACCTRWLYG------LP-----DGRATCRSVPGLTKDQVELCYKASDVTAA 99
            ||...|.|..::.||..:|.|..      ||     .....|.::.||:|.|:.||.::.||||:
Mouse     7 SRPPPLGLAGLLFLALFSRALSNEILGLKLPGEPPLTANTVCLTLSGLSKRQLGLCLRSPDVTAS 71

  Fly   100 ALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASSLLKKGYRESAFAFAISAAGVAHSVARAC 164
            ||:||.:|:.|||.|.:..|||||:|....|.||.|::||:|:|||||:|::.||||.|:||.||
Mouse    72 ALQGLHIAVHECQHQLRDQRWNCSALEGGGRLPHHSAILKRGFRESAFSFSMLAAGVMHAVATAC 136

  Fly   165 SQGRLMSCGC--DPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYERSKIAS---- 223
            |.|:|:||||  ..:..:..|...|.|         ||.|...:.. |..:.......:.|
Mouse   137 SLGKLVSCGCGWKGSGEQDRLRAKLLQ---------LQALSRGKTF-PISQPSPVPGSVPSPGPQ 191

  Fly   224 -RWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNHAGRIAVSNNMEFRCKCHGMSGSC 287
             .|:||||:|:||||.::|:.|||.||...|||:::.:|||..||..|:.|::.:|||||.||||
Mouse   192 DTWEWGGCNHDMDFGEKFSRDFLDSREAPRDIQARMRIHNNRVGRQVVTENLKRKCKCHGTSGSC 256

  Fly   288 QLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARNKKSNGGSGSGSTSPDLD 352
            |.||||::||:|..:|..|:.:..:||.:|..|             ||        ||:..|.|
Mouse   257 QFKTCWRAAPEFRAIGAALRERLSRAIFIDTHN-------------RN--------SGAFQPRL- 299

  Fly   353 STDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKNAARMARKLETSLFYYQRSPNFCERDLG 417
                                           :|          |:|...|.|:::||:|||||..
Mouse   300 -------------------------------RP----------RRLSGELVYFEKSPDFCERDPT 323

  Fly   418 ADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQWCCNVECEECHVEEWISIC 482
            ....||.||.||:.:...|||.||||||||:.:.|.|.|||||:|.|||.|.|:||.|.||:::|
Mouse   324 LGSPGTRGRACNKTSRLLDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDECKVTEWVNVC 388

  Fly   483  482
            Mouse   389  388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	154/390 (39%)
Wnt10b	NP_035848.1	Wnt_Wnt10b	45..389	CDD:381730	166/417 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842343
Domainoid	1	1.000	330	1.000	Domainoid score	I1155
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20721
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2401
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1241694at2759
OrthoFinder	1	1.000	-	-		FOG0004126
OrthoInspector	1	1.000	-	-		otm42627
orthoMCL	1	0.900	-	-		OOG6_107889
Panther	1	1.100	-	-	LDO	PTHR12027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5519
SonicParanoid	1	1.000	-	-		X2869
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790