DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Wnt10 and nek9

DIOPT Version :9

Sequence 1:	NP_609109.3	Gene:	Wnt10 / 34011	FlyBaseID:	FBgn0031903	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	XP_012823572.1	Gene:	nek9 / 100216232	XenbaseID:	XB-GENE-974101	Length:	942	Species:	Xenopus tropicalis

Alignment Length:	328	Identity:	71/328 - (21%)
Similarity:	115/328 - (35%)	Gaps:	106/328 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 GRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYERSKIASRWKWGGCS 231
            |::::||.:.. |:..||:.....::.|..|.:.|  |..:...::...|:...|:.     |.:
Frog   533 GKVLACGLNEH-NKLGLNQYTAGIINHEAFQEVPY--TTSLTLAKQLSFYKIRSISP-----GRT 589

  Fly   232 HN---------MDFGV---------EYSK-LFLD-----------CREKAGD---IQSKINLH-- 261
            |.         :.||.         :|.| |.::           .|...||   |.:..:.|
Frog   590 HTAAIDERGRLLTFGSNKCGQLGVGDYRKHLGINLLGGPLGGKQVIRVSCGDEFTIAATADNHIF 654

  Fly   262 ---NNHAGRIAVSNNMEFRCKCHGMSGSCQLKTCWK-------------SAPDFH---IVGKVLK 307
               |...||:|::.|       ....|| .:.|.|.             |...:|   ||.|||.
Frog   655 AWGNGGNGRLAMTPN-------ERPQGS-DICTSWPRPIFGSLHHVTDLSCRGWHTILIVEKVLN 711

  Fly   308 HQFRKAILVDQSNLGNGEPVVVLKRARNKKSNGGSGSGSTSPDLD----STDASGGHDDGGTGDS 368
               .|.|..:.|.|..|          ....:..|||||...|.:    ::|.|.|.  .||.::
Frog   712 ---SKTIRSNSSGLSIG----------TLAQSCSSGSGSREEDSERESLTSDPSRGF--RGTIEA 761

  Fly   369 ETRRHDELGVERGTRQPSADKNAARMARKLETSLFY-YQRSPNFCERDLGADIQGTVGRKCNRNT 432
            |    .|.|....|....:....:.:.::||.:.|. ...:|||            |..:.::|.
Frog   762 E----PETGPFNTTENMESSSCPSWLRQELEEAEFIPMPDTPNF------------VSMESSQNG 810

  Fly   433 TTS 435
            |||
Frog   811 TTS 813

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	71/328 (22%)
nek9	XP_012823572.1	STKc_Nek9	33..290	CDD:270860
nek9	XP_012823572.1	ATS1	370..708	CDD:227511	37/190 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900