DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Wnt10 and wnt7bb

DIOPT Version :9

Sequence 1:	NP_609109.3	Gene:	Wnt10 / 34011	FlyBaseID:	FBgn0031903	Length:	483	Species:	Drosophila melanogaster
Sequence 2:	XP_001920219.1	Gene:	wnt7bb / 100148840	ZFINID:	ZDB-GENE-081006-1	Length:	352	Species:	Danio rerio

Alignment Length:	408	Identity:	140/408 - (34%)
Similarity:	194/408 - (47%)	Gaps:	99/408 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 CRSVPGLTKDQVELCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASSLLKK 140
            |..:|||...|..:|....|......||..:.|.|||.||::.|||||:|..::   .....|:.
Zfish    42 CNKIPGLAPRQRAICQSRPDAIIVIGEGAQLGINECQYQFRYGRWNCSALGERT---VFGQELRV 103

  Fly   141 GYRESAFAFAISAAGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETN 205
            |.||:||.:||:||||||:|..|||||.:..|||                 |:||:.:..
Zfish   104 GSREAAFTYAITAAGVAHAVTAACSQGNMSHCGC-----------------DREKQGYYN----- 146

  Fly   206 QILTPEEEKKYERSKIASRWKWGGCSHNMDFGVEYSKLFLDCREKAGDIQSKINLHNNHAGRIAV 270
                 :||          .|||||||.::.:|:|:|:.|:|.||...:.:..:|||||.|||..:
Zfish   147 -----QEE----------GWKWGGCSADIKYGIEFSRKFVDAREIKKNARRLMNLHNNEAGRKVL 196

  Fly   271 SNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGEPVVVLKRARN 335
            ...|:..|||||:||||..||||.:.|.|..:|.|||.::.||:.|:           |::.:|
Zfish   197 EERMKLECKCHGVSGSCTTKTCWTTLPKFREIGYVLKDKYNKAVQVE-----------VVRASR- 249

  Fly   336 KKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADK-NAARMARKLE 399
                                                          .|||:..| ...|..:.||
Zfish   250 ----------------------------------------------LRQPTFLKVKRTRHQKPLE 268

  Fly   400 TSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHSQVIQRRAERCHCKFQW 464
            |.|.|.:||||:||.|......||.||.|||.:..:|||..:|||||::.....:..:|:|||||
Zfish   269 TDLVYIERSPNYCEEDAKTGSVGTQGRLCNRTSPHTDGCDLMCCGRGYNTHQYTKVWQCNCKFQW 333

  Fly   465 CCNVECEECHVEEWISIC 482
            ||.|:|..|.....:..|
Zfish   334 CCFVKCNTCSERTEVFTC 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt10	NP_609109.3	wnt	82..466	CDD:278536	131/384 (34%)
wnt7bb	XP_001920219.1	wnt	48..352	CDD:278536	137/402 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740