DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wnt6 and wnt11f2

DIOPT Version :9

Sequence 1:	NP_001260188.1	Gene:	Wnt6 / 34010	FlyBaseID:	FBgn0031902	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001138276.1	Gene:	wnt11f2 / 791595	ZFINID:	ZDB-GENE-990603-12	Length:	353	Species:	Danio rerio

Alignment Length:	421	Identity:	128/421 - (30%)
Similarity:	188/421 - (44%)	Gaps:	98/421 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLMVIAILIFAMPMTGFGW----AEGTNILLDPNLMCKKTRRLRGKLAEICRHDSALLKEIIING 63
            ||:.|..|....|.||..|    ..|:::..:....||....|.....::|:.:..|:.. |:..
Zfish     8 LLLFITSLSVIYPCTGISWLGLTINGSSVGWNQTHHCKLLDGLVPDQQQLCKRNLELMHS-IVRA 71

  Fly    64 INLGFRECEFQFRNRRWNCTVLRKS--MRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVE 126
            ..|....|...|.:.||||:.:..:  ....|.:.:||..||.::.||.|::|:.:||..|.|..
Zfish    72 ARLTKSACTSSFSDMRWNCSSIESAPHFTPDLAKGTREAAFVFSLAAAVVSHAIARACASGDLPS 136

  Fly   127 CSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAP 191
            |||                             |||           ||::            .||
Zfish   137 CSC-----------------------------AAM-----------PSEQ------------AAP 149

  Fly   192 VEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRS--DLG 254
                                         .:.||||.||:.:||:....|.||..|.|||  ...
Zfish   150 -----------------------------DFRWGGCGDNLRYGLQMGSAFSDAPIRNRRSGPQAF 185

  Fly   255 TLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRN 319
            .|::.|||..||..:.|::.::|||||:||||:|||||..:.....::..|:.:|.||.||..|.
Zfish   186 RLMQLHNNAVGRQVLMDSLEMKCKCHGVSGSCSVKTCWKGLQDISTISADLKSKYLSATKVIPRQ 250

  Fly   320 DG--NSFMPESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNR 382
            .|  ...:|.....||..:.:||:...|||:||.|:|.|:|||..|:||.|:|||:.|..:||.|
Zfish   251 IGTRRQLVPREMEVRPVGENELVYLVSSPDYCTQNAKQGSLGTTDRQCNKTASGSESCGLMCCGR 315

  Fly   383 G---HTRRIVEEQTNCKCVFKWCCEVTCEKC 410
            |   :|..:||   .|:|.:.|||.|:|:.|
Zfish   316 GYNAYTEVLVE---RCQCKYHWCCYVSCKTC 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	117/379 (31%)
wnt11f2	NP_001138276.1	wnt	50..353	CDD:278536	117/379 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810