Protein Alignment Wnt6 and WNT7B

DIOPT Version :9

• Sequence 1: NP_001260188.1
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: XP_011528668.1
• Gene: WNT7B / 7477
• HGNCID: 12787
• Length: 353
• Species: Homo sapiens
• Alignment Length: 427
• Identity: 142/427 - (33%)
• Similarity: 197/427 - (46%)
• Gaps: 94/427 - (22%)

  Fly     3 LLMVIAILIFAMPMTGFGWAEGTNILLDPNLMCKKTRRLRGKLAEIC--RHDSALLKEIIINGIN 65
            |:.|....||.:..:|...|..:.:.|..|::|.|...|..:...||  |.|:.:   :|..|..
Human    10 LVSVYCPQIFLLLSSGSYLALSSVVALGANIICNKIPGLAPRQRAICQSRPDAII---VIGEGAQ 71

  Fly    66 LGFRECEFQFRNRRWNCTVL--RKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECS 128
            :|..||::|||..||||:.|  :....:.|...|||..|..|||||||.:|||.||:.|.|..|.
Human    72 MGINECQYQFRFGRWNCSALGEKTVFGQELRVGSREAAFTYAITAAGVAHAVTAACSQGNLSNCG 136

  Fly   129 CDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVE 193
            ||:                                                             |
Human   137 CDR-------------------------------------------------------------E 140

  Fly   194 HRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVK 258
            .:|..|:..|                  |:|||||.:|.:|:..||.|:||  |:.:.:...|:.
Human   141 KQGYYNQAEG------------------WKWGGCSADVRYGIDFSRRFVDA--REIKKNARRLMN 185

  Fly   259 FHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRNDGNS 323
            .|||.|||..:.|.|:|||||||:|||||.||||..:|.||||...|:::|::|.:|.:......
Human   186 LHNNEAGRKVLEDRMQLECKCHGVSGSCTTKTCWTTLPKFREVGHLLKEKYNAAVQVEVVRASRL 250

  Fly   324 FMPESPHARPANKYQ------LVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNR 382
            ..|.....:....||      ||:.:.||::|..::.||::|||||.||.||.|:|.||.:||.|
Human   251 RQPTFLRIKQLRSYQKPMETDLVYIEKSPNYCEEDAATGSVGTQGRLCNRTSPGADGCDTMCCGR 315

  Fly   383 GHTRRIVEEQTNCKCVFKWCCEVTCEKCLEHRAVNTC 419
            |:......:...|.|.|.|||.|.|..|.|...|.||
Human   316 GYNTHQYTKVWQCNCKFHWCCFVKCNTCSERTEVFTC 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	130/387 (34%)
WNT7B	XP_011528668.1	wnt_Wnt7b	36..353	CDD:381724	136/401 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810