Protein Alignment Wnt6 and WNT7A

DIOPT Version :9

• Sequence 1: NP_001260188.1
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 138/404 - (34%)
• Similarity: 192/404 - (47%)
• Gaps: 96/404 - (23%)

  Fly    27 ILLDPNLMCKKTRRLRGKLAEIC--RHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVL--RK 87
            :.|..:::|.|...|..:...||  |.|:.:   :|..|..:|..||:|||||.||||:.|  |.
Human    30 VALGASIICNKIPGLAPRQRAICQSRPDAII---VIGEGSQMGLDECQFQFRNGRWNCSALGERT 91

  Fly    88 SMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAA 152
            ...|.|...|||..|..||.||||.:|:|.|||.|.|.:|.|||
Human    92 VFGKELKVGSREAAFTYAIIAAGVAHAITAACTQGNLSDCGCDK--------------------- 135

  Fly   153 LERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKF 217
             |:|.|                                  .||
Human   136 -EKQGQ----------------------------------YHR---------------------- 143

  Fly   218 PEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGL 282
            .|| |:|||||.::.:|:..::||:||  |:.:.:..||:..|||.|||..:.:.|:|||||||:
Human   144 DEG-WKWGGCSADIRYGIGFAKVFVDA--REIKQNARTLMNLHNNEAGRKILEENMKLECKCHGV 205

  Fly   283 SGSCTVKTCWLKMPPFREVAGRLRDRYDSARKV----TLRNDGNSFMP-ESP--HARPANKYQLV 340
            |||||.||||..:|.|||:...|:|:|:.|..|    ..||...:|:. :.|  :.:|.:. .||
Human   206 SGSCTTKTCWTTLPQFRELGYVLKDKYNEAVHVEPVRASRNKRPTFLKIKKPLSYRKPMDT-DLV 269

  Fly   341 FADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFKWCCEV 405
            :.:.||::|..:..||::|||||.||.|:..:..||.:||.||:..........|.|.|.|||.|
Human   270 YIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV 334

  Fly   406 TCEKCLEHRAVNTC 419
            .|..|.|...:.||
Human   335 KCNTCSERTEMYTC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	133/388 (34%)
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	138/402 (34%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		6/27 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810