Protein Alignment Wnt6 and WNT3

DIOPT Version :10

• Sequence 1: NP_609108.3
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_110380.1
• Gene: WNT3 / 7473
• HGNCID: 12782
• Length: 355
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 139/404 - (34%)
• Similarity: 191/404 - (47%)
• Gaps: 109/404 - (26%)

  Fly    33 LMCKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKSMR---KILM 94
            |:|.....|..|....||:...::.. :..|:.||.:||:.|||.||||||.:..|:.   .:|.
Human    43 LLCGSIPGLVPKQLRFCRNYIEIMPS-VAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLD 106

  Fly    95 RDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQA 159
            :.:||:.||:||.:|||.:|||::|..|....|.||..|
Human   107 KATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHH-------------------------- 145

  Fly   160 AMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQ-WE 223
                                                                    |.|.|: |:
Human   146 --------------------------------------------------------KGPPGEGWK 154

  Fly   224 WGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTV 288
            |||||::.:||:..||.|.||  |:.|.|..:.:..|||.|||..|.|.|.|:||||||||||.|
Human   155 WGGCSEDADFGVLVSREFADA--RENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEV 217

  Fly   289 KTCWLKMPPFREVAGRLRDRYDSARKV-------------TLRNDGNSFMPESPHARPANKYQLV 340
            ||||...|.||.:...|:|:||||.::             |||...:.|       :|..:..||
Human   218 KTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYSLF-------KPPTERDLV 275

  Fly   341 FADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFKWCCEV 405
            :.::||:||.||.:||:.||:.|.|||||.|.|.||.|||.|||..|..:.:..|.|:|.|||.|
Human   276 YYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYV 340

  Fly   406 TCEKCLEHRAVNTC 419
            :|::|:....|:||
Human   341 SCQECIRIYDVHTC 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_609108.3	Wnt_Wnt6	29..420	CDD:381712	139/404 (34%)
WNT3	NP_110380.1	Wnt_Wnt3_Wnt3a	42..355	CDD:381709	139/404 (34%)