DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wnt6 and wnt7aa

DIOPT Version :9

Sequence 1:	NP_001260188.1	Gene:	Wnt6 / 34010	FlyBaseID:	FBgn0031902	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_001020711.1	Gene:	wnt7aa / 565714	ZFINID:	ZDB-GENE-051129-1	Length:	349	Species:	Danio rerio

Alignment Length:	419	Identity:	139/419 - (33%)
Similarity:	193/419 - (46%)	Gaps:	98/419 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IFAMPMTGFGWAEGTNILLDPNLMCKKTRRLRGKLAEIC--RHDSALLKEIIINGINLGFRECEF 73
            |..:.:.||    .:.:.|..:::|.|...|..:...||  |.|:.:   :|..|..:|..||:|
Zfish    18 IIYLKIGGF----SSVVALGASIICNKIPGLAPRQRTICQSRPDAII---VIGEGAQMGINECQF 75

  Fly    74 QFRNRRWNCTVL--RKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRR 136
            ||:|.||||:.|  |....|.|...|:|..|..||.||||.:|:|.|||.|.|..|.|||
Zfish    76 QFKNGRWNCSALGERTVFGKELKVGSKEAAFTYAIIAAGVAHAITAACTQGTLSGCGCDK----- 135

  Fly   137 NGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRR 201
                                                                    |.:|..|:.
Zfish   136 --------------------------------------------------------EKQGFYNQE 144

  Fly   202 PGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGR 266
            .|                  |:|||||.::.:||..|:|||||  |:.:.:..||:..|||..||
Zfish   145 EG------------------WKWGGCSADIRYGLSFSKVFLDA--REIKQNARTLMNLHNNEVGR 189

  Fly   267 LAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKV----TLRNDGNSFMP- 326
            ..:...|||||||||:|||||.||||..:|.||::...|::||:.|..|    ..||...:|:.
Zfish   190 KILEKNMRLECKCHGVSGSCTTKTCWTTLPKFRQLGYILKERYNHAVHVEPVRASRNKRPAFLKV 254

  Fly   327 ESPHA-RPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVE 390
            :.|:: |......||:.:.||::|..:..||::|||||.||.|:..::.||.:||.||:......
Zfish   255 KKPYSYRKPMDTDLVYIEKSPNYCEADPVTGSMGTQGRICNKTAQHTNGCDLMCCGRGYNTHQYS 319

  Fly   391 EQTNCKCVFKWCCEVTCEKCLEHRAVNTC 419
            ....|.|.|.|||.|.|..|.|...|.||
Zfish   320 RVWQCNCKFLWCCYVKCNTCSERTEVYTC 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	131/387 (34%)
wnt7aa	NP_001020711.1	wnt	44..349	CDD:278536	133/389 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26044
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810