Protein Alignment Wnt6 and WNT4

DIOPT Version :9

• Sequence 1: NP_001260188.1
• Gene: Wnt6 / 34010
• FlyBaseID: FBgn0031902
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: XP_011539899.1
• Gene: WNT4 / 54361
• HGNCID: 12783
• Length: 373
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 132/391 - (33%)
• Similarity: 197/391 - (50%)
• Gaps: 89/391 - (22%)

  Fly    35 CKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRK--SMRKILMRDS 97
            |:|.:.|..:..::|:.:..:: :.:..|..|...||::|||||||||:.|..  ...|::.:.:
Human    65 CEKLKGLIQRQVQMCKRNLEVM-DSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGT 128

  Fly    98 RETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAML 162
            ||..||.||::|||.:|||:||:.|:|.:|.||:
Human   129 REAAFVYAISSAGVAFAVTRACSSGELEKCGCDR------------------------------- 162

  Fly   163 RQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGC 227
                                  |:..::                           |:| ::|.||
Human   163 ----------------------TVHGVS---------------------------PQG-FQWSGC 177

  Fly   228 SDNVNFGLRHSRVFLDAKQRQR-RSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTC 291
            |||:.:|:..|:.|:|.::|.: .|....|:..|||.|||.||...||:||||||:||||.||||
Human   178 SDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTC 242

  Fly   292 WLKMPPFREVAGRLRDRYDSARKVTLRNDGNS--FMPESPHARPANKYQLVFADDSPDFCTPNSK 354
            |..:||||:|...|::::|.|.:|..|..|:|  .:|.:...:|.....||:.:.|||||..:.:
Human   243 WRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMR 307

  Fly   355 TGALGTQGRECNVTSSGSDRCDRLCCNRG-HTRRIVEEQTNCKCVFKWCCEVTCEKCLEHRAVNT 418
            :|.|||:||.||.||...|.|:.|||.|| ||.: ||....|.|.|.|||.|.|.:|.....::|
Human   308 SGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQ-VELAERCSCKFHWCCFVKCRQCQRLVELHT 371

  Fly   419 C 419
            |
Human   372 C 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt6	NP_001260188.1	wnt	41..419	CDD:278536	128/383 (33%)
WNT4	XP_011539899.1	wnt	71..373	CDD:278536	130/385 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810