DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt6 and Wnt4

DIOPT Version :9

Sequence 1:NP_001260188.1 Gene:Wnt6 / 34010 FlyBaseID:FBgn0031902 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_001260187.1 Gene:Wnt4 / 34007 FlyBaseID:FBgn0010453 Length:539 Species:Drosophila melanogaster


Alignment Length:397 Identity:113/397 - (28%)
Similarity:170/397 - (42%) Gaps:125/397 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 NLMCKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKSMRKILMRD 96
            |..|:|...|.|.|:|..|               |....||.|||..||||::..:..|.|..:.
  Fly   250 NHQCRKETGLPGTLSEARR---------------LATTHCEEQFRYDRWNCSIETRGKRNIFKKL 299

  Fly    97 SRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAM 161
            .:||.||:|:|||.:|:::.:||..|::.:|||                                
  Fly   300 YKETAFVHALTAAAMTHSIARACAEGRMTKCSC-------------------------------- 332

  Fly   162 LRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQ-WEWG 225
                                        .|.:|    ||                  |.| ::||
  Fly   333 ----------------------------GPKKH----NR------------------EAQDFQWG 347

  Fly   226 GCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKT 290
            ||:||:..|.|.:|.|||.  |....|..:.:..|::..|..|:...|..:|||||:||||::||
  Fly   348 GCNDNLKHGKRVTRSFLDL--RGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKT 410

  Fly   291 CWLKMPPFREVAGRLRDRYDSA-RKV----TLRNDGNSFM--PESPHARP-ANKY-QLVFADDSP 346
            ||.||..|...|..||.:|:.| ||.    ::|...:|.|  |:....:| .::| .|.:.:.||
  Fly   411 CWKKMADFNATATLLRQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSP 475

  Fly   347 DFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFK--WCCEVTCEK 409
            .:|..        |:.|:|    ...|.|..|||.||:|.::|::...|:|.|.  .||::.|:.
  Fly   476 SYCAV--------TKDRQC----LHPDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDY 528

  Fly   410 C--LEHR 414
            |  ||::
  Fly   529 CQRLENK 535

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt6NP_001260188.1 wnt 41..419 CDD:278536 110/388 (28%)
Wnt4NP_001260187.1 wnt 246..539 CDD:278536 113/397 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45456817
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D280593at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR12027
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
54.850

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