Protein Alignment wg and WNT10A

DIOPT Version :9

• Sequence 1: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_079492.2
• Gene: WNT10A / 80326
• HGNCID: 13829
• Length: 417
• Species: Homo sapiens
• Alignment Length: 459
• Identity: 152/459 - (33%)
• Similarity: 213/459 - (46%)
• Gaps: 121/459 - (26%)

  Fly    47 PNNITPI-MYMDPAIHST--------LRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNRRW 102
            ||:|..: :..:|.:::.        |.|:|..:...:|.|..:.::|..:||.|||||||::||
Human    41 PNDILDLRLPPEPVLNANTVCLTLPGLSRRQMEVCVRHPDVAASAIQGIQIAIHECQHQFRDQRW 105

  Fly   103 NCSTRNFSRGKNLF-GKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRS-- 164
            |||:.. :|.|..: ..|..||.||::|.|||.:|.|.|:::.||:.|.:::|.||.|.:...
Human   106 NCSSLE-TRNKIPYESPIFSRGFRESAFAYAIAAAGVVHAVSNACALGKLKACGCDASRRGDEEA 169

  Fly   165 -----------------------PQANHQAGSVA--GVRD-WEWGGCSDNIGFGFKFSREFVDTG 203
                                   |:  |.|...|  |::| |||||||.::|||.:||::|:|:.
Human   170 FRRKLHRLQLDALQRGKGLSHGVPE--HPALPTASPGLQDSWEWGGCSPDMGFGERFSKDFLDSR 232

  Fly   204 ERGRNLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGA 268
            |..|::..:|.||||..||..|...||::|||||.||||.:||||.....||.:|..|::||..|
Human   233 EPHRDIHARMRLHNNRVGRQAVMENMRRKCKCHGTSGSCQLKTCWQVTPEFRTVGALLRSRFHRA 297

  Fly   269 TRVQVTNSLRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPI 333
            |.::..|    .|. ..:.|..||:.|..
Human   298 TLIRPHN----RNG-GQLEPGPAGAPSPA------------------------------------ 321

  Fly   334 SKIHHPNMPSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCE 398
                 |..|.|              ||:.                    ...||||.|.||.|||
Human   322 -----PGAPGP--------------RRRA--------------------SPADLVYFEKSPDFCE 347

  Fly   399 KNLRQGILGTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKV 463
            :..|....||.||.||::|.|.||||.||||||:........|||.|.|||||.|.|:.||..:.
Human   348 REPRLDSAGTVGRLCNKSSAGSDGCGSMCCGRGHNILRQTRSERCHCRFHWCCFVVCEECRITEW 412

  Fly   464 IYTC 467
            :..|
Human   413 VSVC 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	148/433 (34%)
WNT10A	NP_079492.2	Wnt	58..417	CDD:393294	148/442 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..331		11/90 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810