Protein Alignment wg and WNT2B

DIOPT Version :9

• Sequence 1: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 154/434 - (35%)
• Similarity: 212/434 - (48%)
• Gaps: 118/434 - (27%)

  Fly    38 WWGIAKVGEP---NNITPIMYMDPAIHSTLRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRN 99
            ||.|..:|..   :||       |.:.|    :||:|.:..|.::.::.:||...|.|||||||:
Human    60 WWYIGALGARVICDNI-------PGLVS----RQRQLCQRYPDIMRSVGEGAREWIRECQHQFRH 113

  Fly   100 RRWNCSTRNFSRGKNLFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRS 164
            .||||:|  ..|...:||:::.|..||.:|:|||:||.|.|:|.||||:|.:..|:||...:.|.
Human   114 HRWNCTT--LDRDHTVFGRVMLRSSREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRH 176

  Fly   165 PQANHQAGSVAGVRDWEWGGCSDNIGFGFKFSREFVDTGE-RGRNLREKMNLHNNEAGRAHVQAE 228
               :.|.|      |::||||||||.:|.:|::.|||..| |.::.|..||||||..||..|:..
Human   177 ---HDQRG------DFDWGGCSDNIHYGVRFAKAFVDAKEKRLKDARALMNLHNNRCGRTAVRRF 232

  Fly   229 MRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRVQVTNSLRATNALAPVSPNAAGS 293
            ::.||||||:|||||::|||..|::||..||.|:.|:|||.:|..|..               |:
Human   233 LKLECKCHGVSGSCTLRTCWRALSDFRRTGDYLRRRYDGAVQVMATQD---------------GA 282

  Fly   294 NSVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNG 358
            |..                                                     |.::|.|..
Human   283 NFT-----------------------------------------------------AARQGYRRA 294

  Fly   359 RRQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGC 423
            .|                        .||||.:.||.:|..:...|.|||.||.|::||.|.|||
Human   295 TR------------------------TDLVYFDNSPDYCVLDKAAGSLGTAGRVCSKTSKGTDGC 335

  Fly   424 GLMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKVIYTC 467
            .:|||||||....|..|.:|.|.|||||.|:||.||....::||
Human   336 EIMCCGRGYDTTRVTRVTQCECKFHWCCAVRCKECRNTVDVHTC 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	146/405 (36%)
WNT2B	NP_078613.1	wnt	74..380	CDD:306592	150/420 (36%)
		WNT-core domain	107..379		136/374 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810