Protein Alignment wg and WNT7A

DIOPT Version :9

• Sequence 1: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_004616.2
• Gene: WNT7A / 7476
• HGNCID: 12786
• Length: 349
• Species: Homo sapiens
• Alignment Length: 404
• Identity: 138/404 - (34%)
• Similarity: 190/404 - (47%)
• Gaps: 99/404 - (24%)

  Fly    64 LRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNRRWNCSTRNFSRGKNLFGKIVDRGCRETS 128
            |..:||.:.:..|..:..:.:|:.:.:.|||.||||.|||||...   .:.:|||.:..|.||.:
Human    44 LAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALG---ERTVFGKELKVGSREAA 105

  Fly   129 FIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRSPQANHQAGSVAGVRDWEWGGCSDNIGFGF 193
            |.|||.:|.|.|:|..||::|.:..|.||...|.   |.:...|       |:|||||.:|.:|.
Human   106 FTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQG---QYHRDEG-------WKWGGCSADIRYGI 160

  Fly   194 KFSREFVDTGERGRNLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIG 258
            .|::.|||..|..:|.|..||||||||||..::..|:.||||||:|||||.||||..|..||.:|
Human   161 GFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELG 225

  Fly   259 DNLKARFDGATRVQVTNSLRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMP 323
            ..||.:::.|..|:   .:||:....|.
Human   226 YVLKDKYNEAVHVE---PVRASRNKRPT------------------------------------- 250

  Fly   324 DILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLV 388
              .|:...|:|                                            ::.|...|||
Human   251 --FLKIKKPLS--------------------------------------------YRKPMDTDLV 269

  Fly   389 YLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEV 453
            |:|.||::||::...|.:||.||.||:|:....||.||||||||...:...|.:|.|.|||||.|
Human   270 YIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV 334

  Fly   454 KCKLCRTKKVIYTC 467
            ||..|..:..:|||
Human   335 KCNTCSERTEMYTC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	138/404 (34%)
WNT7A	NP_004616.2	Wnt_Wnt7a	32..349	CDD:381723	138/404 (34%)
		Disordered linker. /evidence=ECO:0000269|PubMed:30026314	238..266		8/113 (7%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810