Protein Alignment wg and WNT6

DIOPT Version :9

• Sequence 1: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_006513.1
• Gene: WNT6 / 7475
• HGNCID: 12785
• Length: 365
• Species: Homo sapiens
• Alignment Length: 452
• Identity: 156/452 - (34%)
• Similarity: 213/452 - (47%)
• Gaps: 127/452 - (28%)

  Fly    35 GSMWWGIAKVGEPNNITPIMYMDPAIHSTLRRKQRRLV-------RDNPGVLGALVKGANLAISE 92
            |.:||.   ||.|      :.|||   :::.||.|||.       :..|.|:..|.:||.|.:.|
Human    23 GGLWWA---VGSP------LVMDP---TSICRKARRLAGRQAELCQAEPEVVAELARGARLGVRE 75

  Fly    93 CQHQFRNRRWNCSTRNFSRGKNLFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCD 157
            ||.|||.||||||:.:     ..||:|:.:..|||:|::|||:|..:|::.:|||.|.:..|.|.
Human    76 CQFQFRFRRWNCSSHS-----KAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGCQ 135

  Fly   158 YSHQSRSPQAN---------HQAGSVAGVRDWEWGGCSDNIGFGFKFSREFVDT-GERGR-NLRE 211
            .......|:.:         ..|||..|...||||||.|::.||.:.||.|:|. .:||| ::|.
Human   136 APRGRAPPRPSGLPGTPGPPGPAGSPEGSAAWEWGGCGDDVDFGDEKSRLFMDARHKRGRGDIRA 200

  Fly   212 KMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRVQVTNS 276
            .:.||||||||..|::..|.||||||:||||.::|||.:|..||.:|..|..||.||:||..||.
Human   201 LVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTND 265

  Fly   277 LRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPISKIHHPNM 341
            .:|.                                                            :
Human   266 GKAL------------------------------------------------------------L 270

  Fly   342 PSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCEKNLRQGIL 406
            |:..:|                                ||||..||:|...||.||..|.|.|..
Human   271 PAVRTL--------------------------------KPPGRADLLYAADSPDFCAPNRRTGSP 303

  Fly   407 GTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKVIYTCL 468
            ||.||.||.::..:.||.|:|||||:|::.|.:.|.|.|.|||||.|:|..||.:|.:..||
Human   304 GTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	145/421 (34%)
WNT6	NP_006513.1	wnt	47..364	CDD:278536	141/413 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	140..164		4/23 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D280593at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820