Protein Alignment wg and WNT2

DIOPT Version :9

• Sequence 1: NP_523502.1
• Gene: wg / 34009
• FlyBaseID: FBgn0284084
• Length: 468
• Species: Drosophila melanogaster
• Sequence 2: NP_003382.1
• Gene: WNT2 / 7472
• HGNCID: 12780
• Length: 360
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 153/435 - (35%)
• Similarity: 213/435 - (48%)
• Gaps: 114/435 - (26%)

  Fly    36 SMWWGIAKVGEPNNITPIMYMD--PAIHSTLRRKQRRLVRDNPGVLGALVKGANLAISECQHQFR 98
            |.||.:...|..:.:    ..|  |.:.|:    ||:|...:|.|:.|:.:|.....:|||||||
Human    25 SSWWYMRATGGSSRV----MCDNVPGLVSS----QRQLCHRHPDVMRAISQGVAEWTAECQHQFR 81

  Fly    99 NRRWNCSTRNFSRGKNLFGKIVDRGCRETSFIYAITSAAVTHSIARACSEGTIESCTCDYSHQSR 163
            ..||||:|  ..|..:|||:::.|..||::|:|||:||.|..:|.||||:|.::||:||
Human    82 QHRWNCNT--LDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGEVKSCSCD------ 138

  Fly   164 SPQANHQAGSVAGVRDWEWGGCSDNIGFGFKFSREFVDTGER-GRNLREKMNLHNNEAGRAHVQA 227
             |:....|....|:  ::||||||||.:|.||:|.|||..|| |::.|..||||||.|||..|:.
Human   139 -PKKMGSAKDSKGI--FDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKR 200

  Fly   228 EMRQECKCHGMSGSCTVKTCWMRLANFRVIGDNLKARFDGATRVQVTNSLRATNALAPVSPNAAG 292
            .::|||||||:|||||::|||:.:|:||..||.|..:::||.:|
Human   201 FLKQECKCHGVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQV--------------------- 244

  Fly   293 SNSVGSNGLIIPQSGLVYGEEEERMLNDHMPDILLENSHPISKIHHPNMPSPNSLPQAGQRGGRN 357
                     ::.|.|..:....||.
Human   245 ---------VMNQDGTGFTVANERF---------------------------------------- 260

  Fly   358 GRRQGRKHNRYHFQLNPHNPEHKPPGSKDLVYLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDG 422
                                  |.|...||||.|.||.:|.::...|.|||.||.||.||.|:|.
Human   261 ----------------------KKPTKNDLVYFENSPDYCIRDREAGSLGTAGRVCNLTSRGMDS 303

  Fly   423 CGLMCCGRGYRRDEVVVVERCACTFHWCCEVKCKLCRTKKVIYTC 467
            |.:|||||||....|..:.:|.|.|||||.|:|:.|.....::||
Human   304 CEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRCQDCLEALDVHTC 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wg	NP_523502.1	Wnt_Wnt1	64..468	CDD:381707	146/405 (36%)
WNT2	NP_003382.1	wnt	43..349	CDD:306592	148/413 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40463
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810