DRSC/TRiP Functional Genomics Resources

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Protein Alignment wg and Wnt7a

DIOPT Version :9

Sequence 1:NP_523502.1 Gene:wg / 34009 FlyBaseID:FBgn0284084 Length:468 Species:Drosophila melanogaster
Sequence 2:NP_033553.2 Gene:Wnt7a / 22421 MGIID:98961 Length:349 Species:Mus musculus


Alignment Length:404 Identity:138/404 - (34%)
Similarity:190/404 - (47%) Gaps:99/404 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 LRRKQRRLVRDNPGVLGALVKGANLAISECQHQFRNRRWNCSTRNFSRGKNLFGKIVDRGCRETS 128
            |..:||.:.:..|..:..:.:|:.:.:.|||.||||.|||||...   .:.:|||.:..|.||.:
Mouse    44 LAPRQRAICQSRPDAIIVIGEGSQMGLDECQFQFRNGRWNCSALG---ERTVFGKELKVGSREAA 105

  Fly   129 FIYAITSAAVTHSIARACSEGTIESCTCDYSHQSRSPQANHQAGSVAGVRDWEWGGCSDNIGFGF 193
            |.|||.:|.|.|:|..||::|.:..|.||...|.   |.:...|       |:|||||.:|.:|.
Mouse   106 FTYAIIAAGVAHAITAACTQGNLSDCGCDKEKQG---QYHRDEG-------WKWGGCSADIRYGI 160

  Fly   194 KFSREFVDTGERGRNLREKMNLHNNEAGRAHVQAEMRQECKCHGMSGSCTVKTCWMRLANFRVIG 258
            .|::.|||..|..:|.|..||||||||||..::..|:.||||||:|||||.||||..|..||.:|
Mouse   161 GFAKVFVDAREIKQNARTLMNLHNNEAGRKILEENMKLECKCHGVSGSCTTKTCWTTLPQFRELG 225

  Fly   259 DNLKARFDGATRVQVTNSLRATNALAPVSPNAAGSNSVGSNGLIIPQSGLVYGEEEERMLNDHMP 323
            ..||.:::.|..|:   .:||:....|.                                     
Mouse   226 YVLKDKYNEAVHVE---PVRASRNKRPT------------------------------------- 250

  Fly   324 DILLENSHPISKIHHPNMPSPNSLPQAGQRGGRNGRRQGRKHNRYHFQLNPHNPEHKPPGSKDLV 388
              .|:...|:|                                            ::.|...|||
Mouse   251 --FLKIKKPLS--------------------------------------------YRKPMDTDLV 269

  Fly   389 YLEPSPSFCEKNLRQGILGTHGRQCNETSLGVDGCGLMCCGRGYRRDEVVVVERCACTFHWCCEV 453
            |:|.||::||::...|.:||.||.||:|:....||.||||||||...:...|.:|.|.|||||.|
Mouse   270 YIEKSPNYCEEDPVTGSVGTQGRACNKTAPQASGCDLMCCGRGYNTHQYARVWQCNCKFHWCCYV 334

  Fly   454 KCKLCRTKKVIYTC 467
            ||..|..:..:|||
Mouse   335 KCNTCSERTEMYTC 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wgNP_523502.1 Wnt_Wnt1 64..468 CDD:381707 138/404 (34%)
Wnt7aNP_033553.2 Wnt_Wnt7a 32..349 CDD:381723 138/404 (34%)
Disordered linker. /evidence=ECO:0000250|UniProtKB:O00755 238..266 8/113 (7%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm42540
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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