Protein Alignment Wnt4 and WNT9A

DIOPT Version :9

• Sequence 1: NP_001260187.1
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_003386.1
• Gene: WNT9A / 7483
• HGNCID: 12778
• Length: 365
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 114/325 - (35%)
• Similarity: 184/325 - (56%)
• Gaps: 44/325 - (13%)

  Fly   240 CRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETA 304
            |..:...|:|...||::.|:..||.||..::...|:.|||::||||::|.|.:.::.|:.:||||
Human    59 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQFQFRFERWNCTLEGRYRASLLKRGFKETA 123

  Fly   305 FVHALTAAAMTHSIARACAEGRMTKCSC--GPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLR 367
            |::|:::|.:||::|:||:.|||.:|:|  .|...||||  :|||||.||||:..:..:.||
Human   124 FLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREA--WQWGGCGDNLKYSSKFVKEFL--- 183

  Fly   368 GGDGDEVSEILR-----HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQ 427
               |...|:.||     |::.||::.:.:.:...||||||||||:::|||:::|.|:.....|:.
Human   184 ---GRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKH 245

  Fly   428 KYNEAIRKAPNQRSMRQVSSSRMKKPKQRR----------KKPQQSQYTTLYYLETSPSYCAV-- 480
            ||..|: |..:..:.....:..:..|:.|.          :.|:      |.:|:.|||:|..
Human   246 KYETAL-KVGSTTNEAAGEAGAISPPRGRASGAGGSDPLPRTPE------LVHLDDSPSFCLAGR 303

  Fly   481 ----TKDRQCLHPDNCGTLCCGRGYTTQ--VVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
                |..|:|....||.::|||||:.||  ||.:..:|:.|:    ||.:.|..|.:.|..|.||
Human   304 FSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRW----CCYVECRQCTQREEVYTCK 364

  Fly   540  539
            Human   365  364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_001260187.1	wnt	246..539	CDD:278536	111/317 (35%)
WNT9A	NP_003386.1	Wnt	64..364	CDD:393294	111/318 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..287		2/26 (8%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	226	1.000	Domainoid score	I2521
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3468
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003784
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4229
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.860