Protein Alignment Wnt4 and WNT2B

DIOPT Version :9

• Sequence 1: NP_001260187.1
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_078613.1
• Gene: WNT2B / 7482
• HGNCID: 12781
• Length: 391
• Species: Homo sapiens
• Alignment Length: 321
• Identity: 102/321 - (31%)
• Similarity: 170/321 - (52%)
• Gaps: 33/321 - (10%)

  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY--- 300
            |..:|. ..||...|::...:..::.|..|.....|:.|||:.||||:...| ...:|.::.
Human    72 CDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDR-DHTVFGRVMLRS 135

  Fly   301 -KETAFVHALTAAAMTHSIARACAEGRMTKCSCGP---KKHNREAQDFQWGGCNDNLKHGKRVTR 361
             :|.|||:|:::|.:.|:|.|||::|.::.|||.|   .:|:.:..||.||||:||:.:|.|..:
Human   136 SREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAK 200

  Fly   362 SFLDLRGGDGDEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLL 425
            :|:|.:.....:...::. |::..|..||...:..:||||||||||:::|||:.::||..|...|
Human   201 AFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYL 265

  Fly   426 RQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--------TK 482
            |::|:.|::....|......::         |:..:::..|.|.|.:.||.||.:        |.
Human   266 RRRYDGAVQVMATQDGANFTAA---------RQGYRRATRTDLVYFDNSPDYCVLDKAAGSLGTA 321

  Fly   483 DRQCLH----PDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
            .|.|..    .|.|..:||||||.|..|.:|.:|.|:|:  .||.:.|..|:...:.:.||
Human   322 GRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFH--WCCAVRCKECRNTVDVHTCK 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_001260187.1	wnt	246..539	CDD:278536	98/312 (31%)
WNT2B	NP_078613.1	wnt	74..380	CDD:306592	99/317 (31%)
		WNT-core domain	107..379		93/283 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.770