Protein Alignment Wnt4 and WNT1

DIOPT Version :9

• Sequence 1: NP_001260187.1
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_005421.1
• Gene: WNT1 / 7471
• HGNCID: 12774
• Length: 370
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 103/312 - (33%)
• Similarity: 163/312 - (52%)
• Gaps: 26/312 - (8%)

  Fly   246 TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFV 306
            :|:|....|:..|:..::|...:.|...|:.|||..||||  .|....::|.|:.    :||||:
Human    65 SRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNC--PTAPGPHLFGKIVNRGCRETAFI 127

  Fly   307 HALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDG 371
            .|:|:|.:|||:||:|:||.:..|:|..::......|:.||||:||:..|:...|.|:| .|..|
Human   128 FAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVD-SGEKG 191

  Fly   372 DEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRK 435
            .::..::. |::|.|...|.|:|..:|||||:||||:::|||.::....|...:||.:::.|.|.
Human   192 RDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRV 256

  Fly   436 APNQRSMRQVSSSRMKK--PKQRRKKPQQSQYTTLYYLETSPSYC--------AVTKDRQCLHP- 489
            ....|...:.|.:.:.:  |:....||....  .|.|.|.||::|        |.|..|.|...
Human   257 LYGNRGSNRASRAELLRLEPEDPAHKPPSPH--DLVYFEKSPNFCTYSGRLGTAGTAGRACNSSS 319

  Fly   490 ---DNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
               |.|..||||||:.|:..:..|:|.|.|:  .||.:.|..|......:.|
Human   320 PALDGCELLCCGRGHRTRTQRVTERCNCTFH--WCCHVSCRNCTHTRVLHEC 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_001260187.1	wnt	246..539	CDD:278536	103/312 (33%)
WNT1	NP_005421.1	Wnt_Wnt1	64..370	CDD:381707	103/312 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D280593at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.780