DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt4 and Wnt8b

DIOPT Version :9

Sequence 1:NP_001260187.1 Gene:Wnt4 / 34007 FlyBaseID:FBgn0010453 Length:539 Species:Drosophila melanogaster
Sequence 2:XP_006231504.1 Gene:Wnt8b / 293990 RGDID:1307644 Length:368 Species:Rattus norvegicus


Alignment Length:295 Identity:90/295 - (30%)
Similarity:144/295 - (48%) Gaps:45/295 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly   274 CEEQFRYDRWNC-----SIETRGKRNIFKKLYKETAFVHALTAAAMTHSIARACAEGRMTKCSCG 333
            |:.||.:|||||     .:.:.|.   .:...:|||||||:::|.:.:::.|.|:.|....|.|.
  Rat    71 CKYQFAWDRWNCPERALQLSSHGG---LRSANRETAFVHAISSAGVMYTLTRNCSLGDFDNCGCD 132

  Fly   334 PKKHNR-EAQDFQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKC 397
            ..::.: ..|.:.||||:||:..|:.:::.|:|......|..:.:..|::|.|.:||...|...|
  Rat   133 DSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDALETGQDARAAMNLHNNEAGRKAVKGTMKRTC 197

  Fly   398 KCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIR-----KAPNQRSMRQVSSSRMKKPKQRR 457
            |||||||||:.:|||.::.:|......|::||:.|::     .|.|..:.|...:...:....|.
  Rat   198 KCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVDLLQGAGNSAAGRGAIADTFRSISTRE 262

  Fly   458 KKPQQSQYTTLYYLETSPSYCAV--------TKDRQCLHPD---------NCGTLC--CGRGYTT 503
                      |.:||.||.||..        |:.|:||...         :|..||  ||.....
  Rat   263 ----------LVHLEDSPDYCLENKTLGLLGTEGRECLRRGRALGRWERRSCRRLCGDCGLAVEE 317

  Fly   504 QVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
            :..:.|..|.|:|:  .||.:.|:.|:|...||||
  Rat   318 RRAETVSSCNCKFH--WCCAVRCEQCRRRVTKYFC 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt4NP_001260187.1 wnt 246..539 CDD:278536 90/295 (31%)
Wnt8bXP_006231504.1 WNT1 39..350 CDD:128408 88/293 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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