Protein Alignment Wnt4 and Wnt2

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_006505108.1
• Gene: Wnt2 / 22413
• MGIID: 98954
• Length: 368
• Species: Mus musculus
• Alignment Length: 343
• Identity: 118/343 - (34%)
• Similarity: 174/343 - (50%)
• Gaps: 61/343 - (17%)

  Fly   239 PCRYMPATRRQNH-QCRKETGLPGTLSEARRLA-----------------TTHCEEQFRYDRWNC 285
            |.|||.||...:. .|   ..:||.:|..|:|.                 |..|:.|||..||||
Mouse    34 PDRYMRATGGSSRVMC---DNVPGLVSRQRQLCHRHPDVMRAIGLGVAEWTAECQHQFRQHRWNC 95

  Fly   286 SIETRGKRNIFKKLY----KETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQD--- 343
            :...| ..::|.::.    :|:|||:|:::|.:..:|.|||::|.:..|||.|||.. .|:|
Mouse    96 NTLDR-DHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKG-SAKDSKG 158

  Fly   344 -FQWGGCNDNLKHGKRVTRSFLDLRGGDGDEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSC 406
             |.||||:||:.:|.:..|:|:|.:...|.:...::. |::..|.:||...:..:||||||||||
Mouse   159 TFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSC 223

  Fly   407 SMKTCWKKMADFNATATLLRQKYNEAIRKAPNQRSMR-QVSSSRMKKPKQRRKKPQQSQYTTLYY 470
            :::|||..||||..|...|.:|||.||:...||.... .|::.|.|||.:          ..|.|
Mouse   224 TLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTK----------NDLVY 278

  Fly   471 LETSPSYCAVTKDRQC--------------LHPDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRC 521
            .|.||.||  .:||:.              ...|:|..:||||||.|..|.::.||.|:|:  .|
Mouse   279 FENSPDYC--IRDREAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCECKFH--WC 339

  Fly   522 CQLICDYCQRLENKYFCK 539
            |.:.|..|....:.:.||
Mouse   340 CAVRCQDCLEALDVHTCK 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	112/335 (33%)
Wnt2	XP_006505108.1	Wnt_Wnt2	44..357	CDD:381719	110/331 (33%)