DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Wnt4 and Wnt9a

DIOPT Version :9

Sequence 1:	NP_001260187.1	Gene:	Wnt4 / 34007	FlyBaseID:	FBgn0010453	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_647459.1	Gene:	Wnt9a / 216795	MGIID:	2446084	Length:	365	Species:	Mus musculus

Alignment Length:	330	Identity:	119/330 - (36%)
Similarity:	184/330 - (55%)	Gaps:	54/330 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 CRYMPATRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLYKETA 304
            |..:...|:|...||::.|:..||.||..::...|:.|||::||||::|.|.:.::.|:.:||||
Mouse    59 CDRLKLERKQRRMCRRDPGVAETLVEAVSMSALECQYQFRFERWNCTLEGRYRASLLKRGFKETA 123

  Fly   305 FVHALTAAAMTHSIARACAEGRMTKCSC--GPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDLR 367
            |::|:::|.:||::|:||:.|||.:|:|  .|...||||  :|||||.||||:..:..:.||
Mouse   124 FLYAISSAGLTHALAKACSAGRMERCTCDEAPDLENREA--WQWGGCGDNLKYSSKFVKEFL--- 183

  Fly   368 GGDGDEVSEILR-----HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQ 427
               |...|:.||     |::.||::.:.:.:...||||||||||:::|||:::|.|:.....|:.
Mouse   184 ---GRRSSKDLRARVDFHNNLVGVKVIKAGVETTCKCHGVSGSCTVRTCWRQLAPFHEVGKHLKH 245

  Fly   428 KY----------NEAIRKA-----PNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSY 477
            ||          |||..:|     |..|:    |.|....|..|..:        |.:|:.|||:
Mouse   246 KYETSLKVGSTTNEATGEAGAISPPRGRA----SGSGGGDPLPRTPE--------LVHLDDSPSF 298

  Fly   478 CAV------TKDRQCLHPDNCGTLCCGRGYTTQ--VVKQVEKCRCRFNNGRCCQLICDYCQRLEN 534
            |..      |..|:|....||.::|||||:.||  ||.:..:|:.|:    ||.:.|..|.:.|.
Mouse   299 CLAGRFSPGTAGRRCHREKNCESICCGRGHNTQSRVVTRPCQCQVRW----CCYVECRQCTQREE 359

  Fly   535 KYFCK 539
            .|.||
Mouse   360 VYTCK 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_001260187.1	wnt	246..539	CDD:278536	116/322 (36%)
Wnt9a	NP_647459.1	Wnt	64..364	CDD:393294	116/323 (36%)
Wnt9a	NP_647459.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	254..287		10/36 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	227	1.000	Domainoid score	I2493
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	230	1.000	Inparanoid score	I3435
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003784
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4229
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960