Protein Alignment Wnt4 and lin-44

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001021081.1
• Gene: lin-44 / 171994
• WormBaseID: WBGene00003029
• Length: 348
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 86/308 - (27%)
• Similarity: 136/308 - (44%)
• Gaps: 66/308 - (21%)

  Fly   258 GLPGTLSEARRLAT------TH-----------------CEEQFRYDRWNCSIETRGKRN--IFK 297
            |.|..|..:|.|.:      ||                 |..:.|:.:|:||.......:  :.:
 Worm    52 GCPSDLLHSRALRSIQLACRTHPATVISAFEGVQEGLQNCANRLRFQQWDCSEAGNIMHDPPLLR 116

  Fly   298 KLYKETAFVHALTAAAMTHSIARACAEGRMTKCSCGPKKHNREAQ-DFQWGGCNDNLKHGKRVTR 361
            :.::|::.:.||::|:....:|.|||:|.:..|:|    :|:..| ::::|||...::||...:|
 Worm   117 QGFRESSLIWALSSASAAWGVATACAQGWIDDCAC----NNQMGQNEYEFGGCTHGVQHGITASR 177

  Fly   362 SFLDLRGGDGDEVSEILRHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLR 426
            ..|...|.....:.::.:|:.:.|..|:...::..||||||||||..|||||:.|........|.
 Worm   178 KLLTKVGAVNTLLRKVEKHNLKAGRLAIKKTLISSCKCHGVSGSCQQKTCWKRTATLEHITDYLV 242

  Fly   427 QKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--TKDRQC--- 486
            :||         .|:......|.:|.             |.|.|||.||..|..  ...|.|
 Worm   243 EKY---------ARAKLYTDDSVVKT-------------TDLIYLEASPDVCKAKSVAGRVCAWR 285

  Fly   487 --LHPD-NCGTLCCGRGYTT--QVVKQVEKCRCRFNNGRCCQLICDYC 529
              .|.. :|..||||.|::.  :||:  .||.|.|  ..||.|:|..|
 Worm   286 NETHTQGDCDRLCCGNGFSIRHEVVR--VKCDCEF--VWCCNLVCKDC 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	86/308 (28%)
lin-44	NP_001021081.1	WNT1	64..339	CDD:128408	81/296 (27%)