DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wnt4 and Wnt2b

DIOPT Version :9

Sequence 1:NP_001260187.1 Gene:Wnt4 / 34007 FlyBaseID:FBgn0010453 Length:539 Species:Drosophila melanogaster
Sequence 2:NP_001178777.1 Gene:Wnt2b / 116466 RGDID:69346 Length:391 Species:Rattus norvegicus


Alignment Length:321 Identity:102/321 - (31%)
Similarity:168/321 - (52%) Gaps:33/321 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   240 CRYMPA-TRRQNHQCRKETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY--- 300
            |..:|. ..||...|::...:..::.|..|.....|:.|||:.||||:...| ...:|.:..   
  Rat    72 CDNIPGLVSRQRQLCQRYPDIMRSVGEGAREWIRECQHQFRHHRWNCTTLDR-DHTVFGRAMLRS 135

  Fly   301 -KETAFVHALTAAAMTHSIARACAEGRMTKCSCGP---KKHNREAQDFQWGGCNDNLKHGKRVTR 361
             :|.|||:|:::|.:.|:|.|||::|.::.|||.|   .:|:.:..||.||||:||:.:|.|..:
  Rat   136 SREAAFVYAISSAGVVHAITRACSQGELSVCSCDPYTRGRHHDQRGDFDWGGCSDNIHYGVRFAK 200

  Fly   362 SFLDLRGGDGDEVSEILR-HDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLL 425
            :|:|.:.....:...::. |::..|..||...:..:||||||||||:::|||:.::||..|...|
  Rat   201 AFVDAKEKRLKDARALMNLHNNRCGRTAVRRFLKLECKCHGVSGSCTLRTCWRALSDFRRTGDYL 265

  Fly   426 RQKYNEAIRKAPNQRSMRQVSSSRMKKPKQRRKKPQQSQYTTLYYLETSPSYCAV--------TK 482
            |::|:.|::....|......::         |:..:.:..|.|.|.:.||.||.:        |.
  Rat   266 RRRYDGAVQVTATQDGANFTAA---------RQGYRHATRTDLVYFDNSPDYCVLDKAAGSLGTA 321

  Fly   483 DRQCLH----PDNCGTLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFCK 539
            .|.|..    .|.|..:||||||.|..|.:|.:|.|:|:  .||.:.|..|:...:.:.||
  Rat   322 GRVCSKTSKGTDGCEIMCCGRGYDTTRVTRVTQCECKFH--WCCAVRCKECRNTVDVHTCK 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wnt4NP_001260187.1 wnt 246..539 CDD:278536 98/312 (31%)
Wnt2bNP_001178777.1 wnt 78..380 CDD:278536 98/313 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3913
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
43.770

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