Protein Alignment Wnt4 and wnt1

DIOPT Version :10

• Sequence 1: NP_476972.2
• Gene: Wnt4 / 34007
• FlyBaseID: FBgn0010453
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: XP_002935152.1
• Gene: wnt1 / 100491444
• XenbaseID: XB-GENE-485280
• Length: 372
• Species: Xenopus tropicalis
• Alignment Length: 370
• Identity: 118/370 - (31%)
• Similarity: 181/370 - (48%)
• Gaps: 55/370 - (14%)

  Fly   204 SNT---NNMDMQQGLYNEHFISEHTVMAVFTSQGQV--GGPCRYMP---------ATRRQNHQCR 254
            |||   ||.....|:.|            ..|.|.|  |...:.:|         .:|||....|
 Frog    22 SNTIAVNNSGKWWGIVN------------VASAGNVLPGSDAQPVPLVLDPSLQLLSRRQKRLIR 74

  Fly   255 KETGLPGTLSEARRLATTHCEEQFRYDRWNCSIETRGKRNIFKKLY----KETAFVHALTAAAMT 315
            :..|:..:::.....|...|:.|||..||||...|..:  :|.|:.    :|||||.|:|:|.:|
 Frog    75 QNPGILQSITRGLHSAIRECKWQFRNRRWNCPTGTGNQ--VFGKIINRGCRETAFVFAITSAGVT 137

  Fly   316 HSIARACAEGRMTKCSCGPKKHNREAQDFQWGGCNDNLKHGKRVTRSFLDL--RGGDGDEVSEIL 378
            ||:||:|:||.:..|||..::......|:.||||:||::.|:.:.|.|:|.  ||.|...:..:
 Frog   138 HSVARSCSEGSIESCSCDYRRRGPGGPDWHWGGCSDNIEFGRFIGREFVDSSERGRDLKYLVNL- 201

  Fly   379 RHDSEVGIEAVSSQMMDKCKCHGVSGSCSMKTCWKKMADFNATATLLRQKYNEAIRKA-PNQRSM 442
             |:::.|...|.::|..:|||||:|||||::|||.::..|.:....|:.:::.|.:.. .|..|.
 Frog   202 -HNNQAGRLTVLTEMRQECKCHGMSGSCSLRTCWMRLPPFRSVGDALKDRFDGASKVTYSNNGSN 265

  Fly   443 RQVSSSRMKKPKQRRKKPQQSQYTT--LYYLETSPSYCAV--------TKDRQC----LHPDNCG 493
            |.  .||...|....:.|..:..::  |.|.|.||::|:.        |..|.|    |..|.|.
 Frog   266 RW--GSRSDPPHLEPENPTHALPSSQDLVYFEKSPNFCSASEKNGTPGTTGRICNSTSLGLDGCE 328

  Fly   494 TLCCGRGYTTQVVKQVEKCRCRFNNGRCCQLICDYCQRLENKYFC 538
            .|||||||.::..|..|:|.|.|:  .||.:.|..|...:..:.|
 Frog   329 LLCCGRGYRSRAEKVTERCHCTFH--WCCHVTCLNCTSSQIVHEC 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt4	NP_476972.2	Wnt_Wnt9	245..539	CDD:381715	106/315 (34%)
wnt1	XP_002935152.1	Wnt_Wnt1	65..372	CDD:381707	106/315 (34%)