| Sequence 1: | NP_938023.1 | Gene: | STING1 / 340061 | HGNCID: | 27962 | Length: | 379 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_610525.4 | Gene: | Sting / 36016 | FlyBaseID: | FBgn0033453 | Length: | 343 | Species: | Drosophila melanogaster |
| Alignment Length: | 206 | Identity: | 56/206 - (27%) |
|---|---|---|---|
| Similarity: | 105/206 - (50%) | Gaps: | 33/206 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Human 156 AHGLAWSYYIGYLRLILPE-----LQARIRTYNQHYNNLLRGAVSQRLYILLPLDC---GVPDN- 211
Human 212 -LSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLE--NGQRAGTCVLEYATPLQTLFAMSQ 273
Human 274 YSQAGFSREDRLEQA--KLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSL---SQEVLRHL 333
Human 334 RQEEK--EEVT 342 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| STING1 | NP_938023.1 | Mediates interaction with ZDHHC1 and ZDHHC11. /evidence=ECO:0000269|PubMed:25299331, ECO:0000269|PubMed:28331227 | 1..190 | 16/38 (42%) | |
| TMEM173 | 44..337 | CDD:464441 | 54/197 (27%) | ||
| Cyclic dinucleotide-binding domain (CBD). /evidence=ECO:0000269|PubMed:22705373 | 153..340 | 55/202 (27%) | |||
| C-terminal tail (CTT). /evidence=ECO:0000269|PubMed:22705373 | 340..379 | 1/3 (33%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 341..370 | 0/2 (0%) | |||
| pLxIS motif. /evidence=ECO:0000269|PubMed:25636800 | 363..366 | ||||
| Sting | NP_610525.4 | TMEM173 | 33..335 | CDD:464441 | 54/197 (27%) |
| Blue background indicates that the domain is not in the aligned region. | |||||