Protein Alignment Ndae1 and slc4a1a

DIOPT Version :10

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: NP_938152.1
• Gene: slc4a1a / 84703
• ZFINID: ZDB-GENE-010525-1
• Length: 905
• Species: Danio rerio
• Alignment Length: 984
• Identity: 331/984 - (33%)
• Similarity: 503/984 - (51%)
• Gaps: 171/984 - (17%)

  Fly   106 KQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVKEGD------------EIEWKET 158
            :||..|:|.|       |....|::...:.:       ...:|.||            || |:||
Zfish    43 RQQGEEQPQT-------FTFNRDLEAARNTN-------TNAIKRGDAESYVELNELRGEI-WQET 92

  Fly   159 ARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSA 223
            .||:.|||:......:||:.||:.|:..||.:||:::..|:|:||::..:|..:...:.:.::..
Zfish    93 GRWVGFEENFSPATGQWSQSHVSYLTFKSLIQLRKVMSTGAVLLDVDDSSLSSIGQKMVEQLLLK 157

  Fly   224 GTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIR-SLADMRNHSSSKKKKSNSKHSRPAQNLSS 287
            ..:.|..:|.:. .:|:|.|.|.|       |::. ..||:...:.|..|:
Zfish   158 KEIRPSDRDALV-TILQRKRSQLE-------PVVSPGSADLELQTFSVTKQ-------------- 200

  Fly   288 ITEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERTLSCFIRL 352
              .|.|..                                 .|.|.:|.|.|:.|::.:..|.||
Zfish   201 --RDQVDR---------------------------------VEGSVVLSGVVENLQKPVVAFARL 230

  Fly   353 SQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGV 417
            ..:||:..:.|..:|.||||.|:||..|..::||.|||||.||:|.:|...||.|.....|.:.:
Zfish   231 RDSVVMEGVLEASIPVRFVFFLVGPSHSGMDYHESGRAMAALMADWVFSLEAYLATNERDLYNAM 295

  Fly   418 DEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEV--RKRP--------------PELPKEEVDEEEE 466
            .:|:|...|:||.:......::|......:.:  |.||              |..|:|:
Zfish   296 ADFMDCSIVIPPTDIQDDSMLKPIINFQKKMLHDRVRPYDTRIMVGGKAPTGPAKPRED------ 354

  Fly   467 EARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLL 531
                    .|:|||..|||::.||||:...|:||:.|||..|.:::.||:|||.|||.|||||||
Zfish   355 --------PLARTGLPFGGMVKDIKRRYKHYLSDFTDALDPQVLSAVIFIYFAALSPAITFGGLL 411

  Fly   532 AEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFW 596
            |:.|...|...|.:||..|.|:.:..|:.||:.::|.|||::|||...::||...|::|:..|.|
Zfish   412 ADKTEHMMGVSEMMVSTCVQGVIFCLFAAQPVLVIGFTGPLMVFEEAFFQFCKGYGFEYIVGRVW 476

  Fly   597 IGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCV 661
            :|||:..|.:::.|::.|.||.:|:|||:|.|:.||:.||||:....::.|.|..|:
Zfish   477 VGMWLIVIVVIIMAVEGSFLVRFISRFTQEIFSILISLIFIYETFSKLIKIFKAHPL-------- 533

  Fly   662 CTPPIGSNASVIDYAKYNWDSCES--------YNGTLVGGDCGTPPTE-------NVFLMSVVLC 711
                      :::|...| ||.:.        .|.||......|...|       |..|:|:.|.
Zfish   534 ----------ILNYEHLN-DSLDDPFHPIKKVINVTLHPDGNVTEHHEIIERAYPNTALLSMCLM 587

  Fly   712 AGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSLG-VPTQKLEVPNELK-PTL 774
            .|.|.|:..|:.||.:.:.|..:|:.:.||.|.||||.|...|.|:. ..||||.||..|. ...
Zfish   588 FGCFFIALYLRGFKTSTYLPGPIRRMVGDFGVPIAIFFMIAVDISISDAYTQKLVVPKGLTVSNT 652

  Fly   775 STRGWLIPPFVEKN--PWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFI 837
            |.|||.|.||.||.  |.|.....|.||:|..||||::.|||.:||::.|.|:.||.|:|:||.:
Zfish   653 SARGWFISPFGEKKTFPVWMMFACVVPAMLVFILIFLESQITTLIVSKPERKMVKGSGFHVDLLL 717

  Fly   838 LSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVS 902
            |..|..:.|:.|:||..||||.|:.|.|:|.:.::    |.:||...|.||||:.||:.:.:|||
Zfish   718 LVFLGGVGSLFGVPWLSAATVRSVTHANALTVMTK----GPRPQIERVLEQRVSGILVAVMVGVS 778

  Fly   903 VLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTM 967
            :|:.|:|..|||..|||:|||||:.||.|:|.:||:|::..|.|:.|...::.:||..|:||:|:
Zfish   779 ILMEPILKMIPMTALFGIFLYMGITSLSGIQLWDRMLLLITPKKHHPAVPYVTRVPTMRMHLYTL 843

  Fly   968 IQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKAL-DLVFTRRELKILDDIMPEMTKRAAADDL 1031
            ||:.||.:||::|| |..|:..|.:|::.|.:|..: ..|||..|:|.||           |||.
Zfish   844 IQVMCLALLWVVKS-SNFSLALPFVLILTIPLRMFMTGHVFTVMEMKCLD-----------ADDA 896

  Fly  1032 H-KLDAEDN 1039
            : |.|.||:
Zfish   897 NVKFDDEDD 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	Band_3_cyto	140..1016	CDD:452680	315/924 (34%)
slc4a1a	NP_938152.1	Band_3_cyto	78..904	CDD:452680	319/932 (34%)