DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ndae1 and BOR4

DIOPT Version :9

Sequence 1:	NP_723263.2	Gene:	Ndae1 / 34005	FlyBaseID:	FBgn0259111	Length:	1190	Species:	Drosophila melanogaster
Sequence 2:	NP_001319010.1	Gene:	BOR4 / 838116	AraportID:	AT1G15460	Length:	683	Species:	Arabidopsis thaliana

Alignment Length:	751	Identity:	172/751 - (22%)
Similarity:	304/751 - (40%)	Gaps:	197/751 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   472 EENGLSRTGRLFGGLINDIKRKAPWYISDYKDAL--SMQCVASWIFLYFACLSPIITFGGLLAEA 534
            ||..:..:.|||.|::.|::.:|..|..|:...|  ....:|...:::||...|:|.||..|:..
plant     2 EEERVDSSKRLFRGIVADLRGRALCYKEDWVAGLRSGFGILAPTTYIFFASALPVIAFGEQLSRD 66

  Fly   535 TGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCL---KMGWD-YMTFRF 595
            |...::.:|:|.|..:||:.:....||||.|||...|.::....:|.|.:   ::|.. |:.:..
plant    67 TEGALSTVETLASTALCGVIHSILGGQPLLILGVAEPTVLMYVYLYNFAIGRPELGKQLYLAWAA 131

  Fly   596 WIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDC 660
            |:.:|.|.:..|:..::.:.::...||...|.|..||:.:||.:||:. ||.....|.::.
plant   132 WVCVWTALLLFVMAILNTADIINRFTRVAGELFGMLISVLFIQQAIKG-MVSEFGMPKDED---- 191

  Fly   661 VCTPPIGSNASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFK 725
                      |.::..|:.|    .|...|:|               ::...|  |:.|.||..|
plant   192 ----------SKLEKYKFEW----LYTNGLLG---------------LIFTFG--LLYTALKSRK 225

  Fly   726 --NALFFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKN 788
              :..:.....|.:|:|:.|.:.:...:...:|         .|::|...:..|  |..|.
plant   226 ARSWRYGTGWYRSFIADYGVPLMVVVWTALSFS---------TPSKLPSGVPRR--LFSPL---- 275

  Fly   789 PW-------WSAI------------IAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLD 834
            ||       |:.|            .|..|||:...|.|.|..:.:.:..:||..|||...||.|
plant   276 PWDSPSLSHWTVIKDMGKVSPGYIFAAFIPALMIAGLYFFDHSVASQLAQQKEFNLKKPSAYHYD 340

  Fly   835 LFILSILIAICSMMGLPWFVAATVLSINHVNSLKL-------------------ESECSA----- 875
            :.:|..:..||.::|||........|..|..||.:                   :.|.|:
plant   341 ILLLGFMTLICGLLGLPPSNGVLPQSPMHTKSLAVLKRQLIRRKMVKTAKESIRKRETSSQVYEN 405

  Fly   876 --------------------------------------------PGEKPQ-----FLGVR--EQR 889
                                                        .|..|:     :|.||  |||
plant   406 MQEVFIEMDKSPLAQTDPSVIIELQDLKEAVMKSNDEEREGDEESGFDPEKHLDAYLPVRVNEQR 470

  Fly   890 VTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYM-- 952
            |:::|..|.:..:||..|.:..||..:|:|.|.||.:.||.|.|||:|:.::|:|...:...:
plant   471 VSNLLQSLLVAGAVLAMPAIKLIPTSILWGYFAYMAIDSLPGNQFFERLTLLFVPTSRRFKVLEG 535

  Fly   953 ----FLRQVPIKRVHLFTMIQL----ACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTR 1009
                |:.:||.|.:..||::|:    .|..:.|:    ....|:||:...::|.||:.
plant   536 AHASFVEKVPYKSMAAFTLLQIFYFGLCYGVTWI----PVAGIMFPVPFFLLIAIRQY------- 589

  Fly  1010 RELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAG---ANYNADKS------GPTTIHI 1065
                    |:|::...|   .|.:|||.:  ::..||:...   .::.::.|      |...|..
plant   590 --------ILPKLFNPA---HLRELDAAE--YEEIPGTPRNPLELSFRSNDSKRGVQEGDAEILD 641

  Fly  1066 PLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNG 1101
            .|:.::...|..|:|:.::..|:....::: |.|:|
plant   642 ELTTSRGELKVRTLNLNEDKGNQIYPKEKV-KAGDG 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	ae	140..1016	CDD:273290	152/655 (23%)
		Band_3_cyto	167..435	CDD:284893
		HCO3_cotransp	476..968	CDD:279322	141/599 (24%)
BOR4	NP_001319010.1	Xan_ur_permease	9..555	CDD:390063	141/596 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1016
orthoMCL	1	0.900	-	-		OOG6_100185
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X102
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720