DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ndae1 and AT3G62270

DIOPT Version :9

Sequence 1:	NP_723263.2	Gene:	Ndae1 / 34005	FlyBaseID:	FBgn0259111	Length:	1190	Species:	Drosophila melanogaster
Sequence 2:	NP_191786.1	Gene:	AT3G62270 / 825400	AraportID:	AT3G62270	Length:	703	Species:	Arabidopsis thaliana

Alignment Length:	777	Identity:	176/777 - (22%)
Similarity:	307/777 - (39%)	Gaps:	183/777 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   483 FGGLINDIKRKAPWYISDYKDAL--SMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESL 545
            |.|:.||:|.:...|..|:...:  ..:.:|...:::||...|:|:||..|..:|...:.|:::|
plant     8 FEGIKNDLKGRLMCYKQDWTGGIKAGFRILAPTTYIFFASAIPVISFGEQLERSTDGVLTAVQTL 72

  Fly   546 VSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCL---KMGWD-YMTFRFWIGMWVAGICI 606
            .|..:||:.:....||||.|||...|.::..:.::.|..   ::|.: ::.:..|:.:|.:.|..
plant    73 ASTAICGIIHSIIGGQPLLILGVAEPTVIMYTFMFNFAKGRPELGRNLFLAWSGWVCVWTSLILF 137

  Fly   607 VLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSNAS 671
            ||....|.:.:...||...|.|..|||.:|:.:||             :|:.| ....|...:..
plant   138 VLAICGACSFINRFTRVAGELFGLLIAMLFMQQAI-------------KGLVD-EFRAPAREDLK 188

  Fly   672 VIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQ 736
            ::::.. :|   ...||                :.::||..|..:.:...::.::..:....:|.
plant   189 LVEFLP-SW---RFANG----------------MFALVLSFGLLITALRSRKARSWRYGTGWLRS 233

  Fly   737 YISDFSVLIAIF---AMSFF---DYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAII 795
            .::|:.|.:.:.   .:|:.   |...|:| ::|..||...|. :...|.:...:.:.|....|.
plant   234 LVADYGVPLMVLVWTGVSYIPTGDVPKGIP-RRLFSPNPWSPG-AYENWTVVKEMLQVPIVYIIG 296

  Fly   796 AVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLS 860
            |..||.:..:|.:.|..:.:.:..:||..|:|...||.||.:|..|..:|.::|:|........|
plant   297 AFIPATMIAVLYYFDHSVASQLAQQKEFNLRKPSSYHYDLLLLGFLTLMCGLLGIPPSNGVIPQS 361

  Fly   861 INHVNSLK------LESECSAPGEK------------------------------PQ-------- 881
            ..|..||.      |.:...|...|                              ||
plant   362 PMHTKSLATLKYQLLRNRLVATARKSIKQNASLGQLYGNMQDVYNQMQTPLVYQQPQGLKELRES 426

  Fly   882 ------FLG------------------------VREQRVTHILIFLTIGVSVLLTPLLGNIPMPV 916
                  |.|                        |:||||:::|..:.:|..|...|||..||..|
plant   427 TIQATTFTGNLDAPVDETLFDIEKEIDDLLPIEVKEQRVSNLLQAVMVGGCVAAMPLLKMIPTSV 491

  Fly   917 LFGVFLYMGVASLKGLQFFDRILIMF-MPA---KYQPD--YMFLRQVPIKRVHLFTMIQ----LA 971
            |:|.|.:|.:.||.|.||::|||::| .|:   |...|  ..|:..||.|.:.:||:.|    |.
plant   492 LWGYFAFMAIESLPGNQFWERILLLFTAPSRRFKVLEDNHATFVETVPFKTIAMFTIFQTTYLLT 556

  Fly   972 CLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDA 1036
            |..:.|:    ....::|||:::.:|.:|:.               |:|...|.|...||...:.
plant   557 CFGLTWI----PIAGVMFPLLIMFLIPVRQY---------------ILPRFFKSAHLQDLDAAEY 602

  Fly  1037 EDN-----HHQHPPGS-GAGANYNADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQI 1095
            |:.     |...|... |:.|:|..|............|....|..|.|.    :...|.|:
plant   603 EEAPALPFHLAVPEAEMGSTASYPCDSEILDEFITRSRGEFRHTCSPKVT----SSTSTPVY--- 660

  Fly  1096 NKDGNGISEQLIIPVTLKVRQINGNHAPSSATLSPRLSPMHEADEYSEAPTNSPAHPAGNQQ 1157
                |....|:..|..:.:|          ..:|||||     .:...:|..||.:|:.:.:
plant   661 ----NRNLSQVFSPRVIDLR----------GEMSPRLS-----GKGQNSPKPSPLNPSSSSK 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	ae	140..1016	CDD:273290	144/628 (23%)
		Band_3_cyto	167..435	CDD:284893
		HCO3_cotransp	476..968	CDD:279322	135/576 (23%)
AT3G62270	NP_191786.1	Xan_ur_permease	2..549	CDD:419983	135/576 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1016
orthoMCL	1	0.900	-	-		OOG6_100185
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X102
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720