Protein Alignment Ndae1 and abts-4

DIOPT Version :10

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: NP_001024826.2
• Gene: abts-4 / 180943
• WormBaseID: WBGene00019844
• Length: 956
• Species: Caenorhabditis elegans
• Alignment Length: 1017
• Identity: 234/1017 - (23%)
• Similarity: 439/1017 - (43%)
• Gaps: 133/1017 - (13%)

  Fly    86 GSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGE---------------DVDDGTHV 135
            ||.|...:.....|.|:...:...||...|||...:..:|..               .::|....
 Worm     4 GSPGRHSNKAFSIGSDDGENENVFVEETSTPPKTPLGTLLTNCTEQSPLILPMPTRPRLEDSPVA 68

  Fly   136 SHPLFSEMGMLVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSV 200
            .|.....:.:.....|:..||:.:|:.::|||.|...|...:|||..:.:.:...|:.:.....:
 Worm    69 EHDHHIVVDVFTVNNDDGTWKQASRFARYEEDCEGFDNHLGRPHVPCIPMGTYDALKMVTAKSIL 133

  Fly   201 MLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRN 265
            ...::.::|:...:.:...:|....  |.:.:|:...:            ..|:..|..:..:..
 Worm   134 FPKVQYESLDEFVNFLETKIVDPDV--PKLGEKIAKLI------------NDRIAEIEKMRPLHQ 184

  Fly   266 HSSSKKKKSNSKHSRPAQNLSSITEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPG-- 328
            .:||..:..::.:.:....:......::.:|:|           |....|    |.||::|..
 Worm   185 RNSSSTQSLDASNPQTISTVGIFPRSLLSAPNN-----------LGSLAH----HPMRRLPTSHS 234

  Fly   329 --------------------------AEASNILVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVP 367
                                      .|.|.::.||:..:.......||..:...:..:......
 Worm   235 GLRFGSSFLPQQPVVSQLEPVIWDEDNEISMLVAGEIPHVNVCRFIAIRFVETTAMEKIFPNMTN 299

  Fly   368 TRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEW 432
            .|.:|.|:||......:.::|||:|:::|:........:.:..|.:...::.||....|:.||
 Worm   300 VRHLFFLIGPALENVTYLDLGRALASVVSNPPATTTFDQLKSPDSITKAIERFLAGTVVIAPG-- 362

  Fly   433 DPTIRIEPPAAIPSQEVRK---------RPPELPKEEVDEEEEEARLREENGLSRTGRLFGGLIN 488
                ||:....:.|..:||         ....:..::||.|....:..|| ...:..|||.|:.:
 Worm   363 ----RIDNKNLVRSDLIRKLVNMQGEKTETKIVHPKDVDVERNATKKAEE-AEDKPFRLFSGVTS 422

  Fly   489 DIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGM 553
            |::.:|..|.|||:|..::.......:::...:.|.:|||.::...|...:|..|.|||..:.|:
 Worm   423 DLRNRAKHYFSDYRDGFNISIFTVVFYMFCVTVVPTLTFGAIMGAGTSGLLAVKECLVSQALSGL 487

  Fly   554 GYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVC 618
            .:...|.|||.::..|||.||||..:::|..:...|::..||:.|:::..|.||..|.:.:.|:.
 Worm   488 IWSVLSCQPLLVMSPTGPFLVFEKALFKFTDQNDMDFLEVRFYTGIFLFFISIVGAATNCAHLIH 552

  Fly   619 YITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPIGSNASVIDYAKYNWDSC 683
            |:|.:||:.|..||:.||..:.:|.:                    .:....:.|:..||..::.
 Worm   553 YVTIYTEDIFCALISLIFFSEVVEFI--------------------HLQEEHNSIENLKYYIENA 597

  Fly   684 ESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIF 748
            .:...|.| .||.. ...|.||:.:::...:..|...|::...:.||....|....:|..:.|:.
 Worm   598 ANCTVTEV-KDCAL-SRPNTFLLQLIMVVVSIAIFHYLRQVSRSTFFGRTFRNLCKNFGGIFAVI 660

  Fly   749 AMS----FFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAI-IAVFPALLGTILIF 808
            |:|    ....::||..  :::|..:..:....|..:.|  ...|..|.: ||:..::|..:|||
 Worm   661 AVSIAYRILFQNVGVAV--VDIPVAVGQSRPFDGIFVIP--SAPPTASTLTIALISSILLFVLIF 721

  Fly   809 MDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESEC 873
            ::.:|...:..|:..|||||.|.|.||.::.....:.|::||||...|.|.|:.|:.|| .|.:.
 Worm   722 VETEIPEQMALREGRKLKKGGGLHWDLIVVGFCTLVSSVLGLPWMCPAAVQSLAHITSL-TEYKK 785

  Fly   874 SAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRI 938
            ||||...:...|.||||:.::.:|.:|...:|...|. ||...:||||.|:||.:|:|.:...|:
 Worm   786 SAPGVPSRISHVIEQRVSGMVTYLLLGTFAILGHFLA-IPAATIFGVFFYLGVRNLEGSKMILRL 849

  Fly   939 LIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVV-MIGIRKA 1002
            .:.|:|:||:..:.||...|...:.::|:||......::..||.....:||||.:|. .|.::..
 Worm   850 KLCFLPSKYRGSHKFLEIAPFYTIQIYTVIQYLIAGAMFAAKSSKIGGLLFPLFIVSNAIFVKHG 914

  Fly  1003 LDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHP 1044
            |.::|.:..|:.||           ::|....||:.::.::|
 Worm   915 LSVIFDKELLEALD-----------SEDHDNDDADRDNEENP 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	Band_3_cyto	140..1016	CDD:452680	215/918 (23%)
abts-4	NP_001024826.2	HCO3_cotransp	415..879	CDD:480978	141/491 (29%)