Protein Alignment Ndae1 and Ndae1

DIOPT Version :10

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: XP_061513943.1
• Gene: Ndae1 / 1279145
• VectorBaseID: AGAMI1_003641
• Length: 1296
• Species: Anopheles gambiae
• Alignment Length: 1300
• Identity: 786/1300 - (60%)
• Similarity: 924/1300 - (71%)
• Gaps: 175/1300 - (13%)

  Fly    11 PWTMNSSSGDDEAPKDPRTGGEDFTQQFTENDFEGHRAHTVYVGVHVPG-GRRHSQRRRKHHHSG 74
            ||.|:....|:|||.|||.....||   .:.||||||||||:||||:|| .||||||||..||..
Mosquito    14 PWMMDHGVVDEEAPIDPRLKNRTFT---ADQDFEGHRAHTVFVGVHIPGSSRRHSQRRRHKHHQA 75

  Fly    75 PGGGGGGGGGGGSIGGSGSVGGGAGKDNVSEKQQEVERPV---------------------TPPA 118
            ....|..|..|                      .|.||||                     ||||
Mosquito    76 SRENGDKGSTG----------------------SEAERPVVTIPHVVTQRRISIVDDGESFTPPA 118

  Fly   119 QRVQFILGEDV---DDGT-HVSHPLFSEMGMLVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPH 179
            ||||||||.:|   .||| |.||||||||..|||||||:.|||||||:|||||||||||||||||
Mosquito   119 QRVQFILGGEVGGEGDGTQHESHPLFSEMEELVKEGDEMAWKETARWVKFEEDVEEGGNRWSKPH 183

  Fly   180 VATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRH 244
            |||||||||||||.||:||:|||||||.:||.:|:|||::||::||||...:|||.||||:||:|
Mosquito   184 VATLSLHSLFELRSLLLNGTVMLDMEAVSLEQIAELVCENMVNSGTLPVEARDKVIDALLKRHKH 248

  Fly   245 QHEY-AKKTRLPIIRSLADM-RNHSSSK-------KKKSNSKHSRPAQ----------------- 283
            |||: :||:|||:||||||: :||||||       .|..:|.:|.|..
Mosquito   249 QHEFGSKKSRLPLIRSLADIGKNHSSSKNMPRSSTSKSISSANSFPMHVVSSAPSGMHEEGESAL 313

  Fly   284 ------------------------------------NLSSIT----------------------- 289
                                                |.||.|
Mosquito   314 GPVSPQTALLYGSKDQRGHYLALPTVEDQANTNSPPNSSSATSNGSNPNASGKPPTNGNSGSGKH 378

  Fly   290 ---------EDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGEVDFLERT 345
                     |:|.:||||.||.|..|..||...:||.|||||||||||||||||||||||||::|
Mosquito   379 LTVPGRAAGENMTQSPSNVSMPRNASSGELQNGEHKTNTHFMRKIPPGAEASNILVGEVDFLDKT 443

  Fly   346 LSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEVAYRARKR 410
            ||.|:||:.|.|:||||||||||||:|||||||||..:||||||||||||||||||||||||::|
Mosquito   444 LSAFLRLNTASVMGDLTEVPVPTRFIFILLGPPGSHGSFHEIGRAMATLMSDEIFHEVAYRAKRR 508

  Fly   411 DHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPEL-PKEEVDEEEEEARLREEN 474
            :|||:|:|||||||||||||||||:||||||||||||||||||||. ||||:|||.||.|.|||.
Mosquito   509 EHLLAGIDEFLDAVTVLPPGEWDPSIRIEPPAAIPSQEVRKRPPEKNPKEEIDEELEEQRQREEA 573

  Fly   475 GLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSPIITFGGLLAEATGKHM 539
            |||||||||||||||:|||.|:|:||:||.|||||||||||||||||||||||||||..|||.::
Mosquito   574 GLSRTGRLFGGLINDLKRKTPFYLSDFKDGLSMQCVASWIFLYFACLSPIITFGGLLGTATGNNI 638

  Fly   540 AAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWVAGI 604
            |||||||||||||:|||||||||||||||||||||||:|:||||.|:||||:|||||||.|::.|
Mosquito   639 AAMESLVSGFVCGIGYGFFSGQPLTILGSTGPVLVFETIVYEFCQKVGWDYLTFRFWIGTWISII 703

  Fly   605 CIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQ--GIYDCVCTPPIG 667
            .:||.|:||||||||||||||||||.|||.||||||||||..||:.:|:|.  |.|||.|.||..
Mosquito   704 LVVLVAVDASALVCYITRFTEENFACLIAVIFIYKAIENVFHIGQEYPLNTAGGKYDCACLPPAT 768

  Fly   668 ---SNASVIDYAKYNWDSCESYNGTLVGGDCGTPP-TENVFLMSVVLCAGTFLISTVLKEFKNAL 728
               :..:|..:|:|:..:|::.||||.|.||..|. ..:|||||:||..||::||.:||:|||||
Mosquito   769 HELTPEAVHQWAQYDLRTCKTLNGTLTGADCDKPEYVSDVFLMSIVLFLGTYIISVILKDFKNAL 833

  Fly   729 FFPSIVRQYISDFSVLIAIFAMSFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSA 793
            |||::|||:||||||.||||:|:..|....:.|.||:||:|.|.|:..|||:|.||.|.||.||:
Mosquito   834 FFPAVVRQFISDFSVTIAIFSMTLLDVFTRIATPKLDVPSEFKRTIPDRGWIIMPFHESNPAWSS 898

  Fly   794 IIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATV 858
            .:|:.|||||||||||||||||||:||||:||.||||||||||:|:.||.||:||||||||||||
Mosquito   899 ALAILPALLGTILIFMDQQITAVIINRKEHKLTKGCGYHLDLFVLACLIQICTMMGLPWFVAATV 963

  Fly   859 LSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLY 923
            ||||||||||.|||.:||||||||:||||||||||||||.||.||||||||.:||||||:|||||
Mosquito   964 LSINHVNSLKKESETAAPGEKPQFIGVREQRVTHILIFLMIGCSVLLTPLLSHIPMPVLYGVFLY 1028

  Fly   924 MGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSIL 988
            |||::|||||||||:|||.|||||||||||||||||:||||||||||||..:||||||||.||||
Mosquito  1029 MGVSALKGLQFFDRLLIMLMPAKYQPDYMFLRQVPIRRVHLFTMIQLACFAVLWLIKSFSITSIL 1093

  Fly   989 FPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANY 1053
            ||||||||||:||:||.:||:|||||||||||||||||.|||||:|:..::..||
Mosquito  1094 FPLMLVVMIGVRKSLDYIFTKRELKILDDIMPEMTKRARADDLHQLEDGEDSGQH---------- 1148

  Fly  1054 NADKSGPTTIHIPLSGNKTGTKGPTVNIPQEAVNRTAVWQQINKDGNGISEQLIIPVTLKVRQIN 1118
            :||     .:.:||.......|| .:||.:| ||||.:|:|:| :.|.:..:...||....:|::
Mosquito  1149 SAD-----NLQLPLENGTVNEKG-KINISEE-VNRTTIWKQVN-NCNVLFTKKQTPVKHSQQQLS 1205

  Fly  1119 GNHAPSSATLSPRLSPMHEADEYSEAPTNSPAHPAGNQQQQQQQINNCKEAAKLDGSCSNNSQIS 1183
                 ..:....|||.|.|.||.::.|:...:|....|:.:::...|.:..:....:.||||..|
Mosquito  1206 -----KLSETEKRLSTMREEDEVADEPSRQLSHQKRTQKMKREFWMNSRSGSSNGRANSNNSASS 1265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	Band_3_cyto	140..1016	CDD:452680	663/976 (68%)
Ndae1	XP_061513943.1	None