Protein Alignment Ndae1 and slc4a1

DIOPT Version :9

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: XP_002935581.2
• Gene: slc4a1 / 100486998
• XenbaseID: XB-GENE-986935
• Length: 946
• Species: Xenopus tropicalis
• Alignment Length: 1053
• Identity: 368/1053 - (34%)
• Similarity: 546/1053 - (51%)
• Gaps: 169/1053 - (16%)

  Fly    33 DFTQQ----FTENDFEGH--RAHTVYVGV------HVPGGRRHSQRRR-KHHHSGPGGGGGGGGG 84
            ||:..    :||:..:|.  |..|:|..:      .:.|....::||| |....|
 Frog    21 DFSDSEATPYTESQSDGEQKRRSTLYKFLRQSAFWEIRGSYNLNRRRRMKDKRQG---------- 75

  Fly    85 GGSIGGSGSVGGGAGKDNVSEKQQEVERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGMLVKE 149
                      |....|....|:::|...|..||       |........|.:..::.|:..|..:
 Frog    76 ----------GQYRVKQKPFEEEEEASAPDFPP-------LAPAFIPPRHRTDEVYIELHELTMD 123

  Fly   150 G-DEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLEVMA 213
            . :|:.|.|.|||:|.|||.::...:|.||.::.|:.|||.|:.|....|:|:||:..:.|..::
 Frog   124 AHNEMRWVEAARWLKVEEDYQDDIRQWGKPQISYLTFHSLLEVHRAFQKGTVLLDLAEKTLPGIS 188

  Fly   214 DLVCDHMVSAGTLPPGVKDKVKDALLRRH-RHQHEYAK----KTRLPIIRSLADMRNHSSSKKKK 273
            ..|.|.|:....|.|..:|:|..|||.:| |...|..|    ::..|::.|| :|:.....::||
 Frog   189 SQVIDQMIYEDRLKPQNRDEVLRALLLQHSRPDEEIIKVGDPESGQPLLHSL-EMKTMPEQEQKK 252

  Fly   274 SNSKHSRPAQNLSSITEDMVKSPSNQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNILVGE 338
            |                                  .|:|           ::|..||||.:|||.
 Frog   253 S----------------------------------PLAE-----------RVPENAEASIVLVGC 272

  Fly   339 VDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEIFHEV 403
            |.|||:....|:||.:||.|..:.|||:|.||:|:||||..|..::||:|||::::|::.:|...
 Frog   273 VSFLEQPTLAFVRLKEAVYLDTVLEVPLPIRFLFVLLGPDNSNISYHEVGRAVSSMMAERVFRNE 337

  Fly   404 AYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKR----------PPELPK 458
            .|.|..|..|:..:::||:...||||.:......::....:....:|||          .||:|.
 Frog   338 MYLAEGRQDLIKSLEDFLEYSIVLPPCDSPDGQLLKDLVPVQKNLLRKRYQVEKELGRIKPEIPD 402

  Fly   459 EEVDEEEEEARLREENGLSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLYFACLSP 523
            |.           .|:.|.|||::||||..||:|:.|.|:||..|||:.||:|:.||:|||.|||
 Frog   403 EP-----------PEDPLRRTGKIFGGLARDIRRRYPKYLSDITDALNPQCLAAVIFIYFAALSP 456

  Fly   524 IITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGW 588
            .||||||::|.|.:.|...|.|||..|.|:.:..|..|||.|||.:||:||||...|.||...|.
 Frog   457 AITFGGLMSEKTNRWMGVSELLVSTAVQGVVFCIFGAQPLLILGFSGPLLVFEEAFYNFCESQGI 521

  Fly   589 DYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPV 653
            :|:..|.|||.|:..|.|::.|.:.|.||.:|:|||:|.|:.||:.||||:....::.|....|:
 Frog   522 EYIVGRVWIGFWLILIVIIVVAFEGSFLVRFISRFTQEIFSFLISLIFIYETFAKLVTIFSKHPL 586

  Fly   654 NQGIYDCVCTPPIGSNASVIDYAKYNWDSCESYNGTLVGGDCGTPPTENVFLMSVVLCAGTFLIS 718
             ||.|         :..:.||.||                    .|..|..|:|:||..|.|||:
 Frog   587 -QGHY---------NQTTEIDLAK--------------------APQPNTALLSLVLMFGAFLIA 621

  Fly   719 TVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSFFDYSL-GVPTQKLEVPNEL---KPTLSTRGW 779
            ..|::|||:.|||..:|:.:.||.|.|||..|...||.: ...||||.:|..|   :|  ..|.|
 Frog   622 FFLRQFKNSGFFPGKLRRIVGDFGVPIAILLMVVADYFIKDTYTQKLSLPKGLSVSRP--ENRTW 684

  Fly   780 LIPPF---VEKNPW--WSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYHLDLFILS 839
            .|||.   ...||:  |....:|.||||..|||||:.|||.:||::.|.|..||.|:||||.::.
 Frog   685 FIPPLGFNTVDNPFPIWMMFASVVPALLVFILIFMESQITTLIVSKPERKTIKGSGFHLDLLLIV 749

  Fly   840 ILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKPQFLGVREQRVTHILIFLTIGVSVL 904
            .:..:|::.|:||..|.||.::.|.|:|.:.|:    |:|||...|.|||::..|:.:.:|||:|
 Frog   750 GMGGVCALFGMPWLSATTVRTVTHANALTITSK----GDKPQIERVIEQRISGFLVAILVGVSIL 810

  Fly   905 LTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIKRVHLFTMIQ 969
            :.|:|..||:.||||:||||||.||.|:|.|||||:|..|.||.|:..|:.:|...|:|:||:||
 Frog   811 MEPILTLIPLAVLFGIFLYMGVTSLNGIQLFDRILLMLKPPKYHPNVPFVTRVKTWRMHIFTLIQ 875

  Fly   970 LACLIILWLIKSFSQTSILFPLMLVVMIGIRKAL-DLVFTRRELKILDDIMPEMTKRAAADDLHK 1033
            ..||.:|:.: .|:..|:..|.:|::.:.:|..| ..:|.:.|||.||       ...|:.:|.:
 Frog   876 TLCLAVLFAV-MFTPASLALPFILILTVPVRMFLMPFIFNKLELKCLD-------SEDASVNLEE 932

  Fly  1034 LDAED--NHHQHP 1044
            .:.:|  |..|.|
 Frog   933 EEGQDVYNEVQMP 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	ae	140..1016	CDD:273290	337/901 (37%)
		Band_3_cyto	167..435	CDD:284893	85/272 (31%)
		HCO3_cotransp	476..968	CDD:279322	218/500 (44%)
slc4a1	XP_002935581.2	ae	114..945	CDD:273290	344/931 (37%)
		Band_3_cyto	150..367	CDD:284893	84/262 (32%)
		HCO3_cotransp	409..874	CDD:279322	218/500 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	1	1.000	-	-		FOG0000136
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X102
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010