Protein Alignment Ndae1 and slc4a11

DIOPT Version :9

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: XP_031751114.1
• Gene: slc4a11 / 100486382
• XenbaseID: XB-GENE-482085
• Length: 879
• Species: Xenopus tropicalis
• Alignment Length: 993
• Identity: 246/993 - (24%)
• Similarity: 413/993 - (41%)
• Gaps: 230/993 - (23%)

  Fly   140 FSEMGMLVKEGDE-IEWKETARWIKFEEDVEEGG---NRWSKPHVATLSLHSLFELRRLLVNGSV 200
            |.|.|.|..:.|: .:.||           ||||   ..:...|.:.:|..|:    |..||
 Frog    26 FEETGYLKCDTDDGCDPKE-----------EEGGGGEELFDTVHSSIVSGESI----RFFVN--- 72

  Fly   201 MLDMEAQNLEVMADLVCDHMVSAGTLPPGVKDKVK----DALLRRHRHQHEYAKKTRLPIIRSLA 261
                  .||||......::..|...|....:..:|    :..:|.||....:..|..:.:
 Frog    73 ------VNLEVPQSTTAENESSGCVLLHTSRKYLKLKNFEEEVRAHRDLDGFLAKASIIL----- 126

  Fly   262 DMRNHSSSKKKKSNSKHSRPAQNLSSITEDMVK----SPSNQSMARPGSG---------TELSEQ 313
                             ...|.:|..:..:|:|    .|.|   |.|...         |: |..
 Frog   127 -----------------DETATSLDDVLREMLKHFVEDPEN---AEPSCNFNKIMSTLFTD-SGA 170

  Fly   314 QHKGNTHFMRKIPPG--AEASNI--------LVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPT 368
            ..:||.|.:.....|  |.|:.:        ::..:..|::...|..||.:....|   |.....
 Frog   171 PREGNVHLLSDTIQGVTATATGVQYQQSWLCIICTIKSLQKRHVCISRLERPQNWG---ENSCEV 232

  Fly   369 RFVFILLGPPGSQS--NFHEIGRAMATLMSD-------------EIFHEVAYRARKRDHLLSGVD 418
            |||.::|.||..:|  ...|:||..:|:.||             |.|.|.....|   |||:.|:
 Frog   233 RFVILVLAPPKMKSTKTATEVGRTFSTMFSDINFRQKLLETKTEEEFKEALVHQR---HLLTLVN 294

  Fly   419 EFLDAVTVLPPGEWDPT------IRIEPPAAIPSQEVRKRPPELPKEEVDEEEEEARLREENGLS 477
            :.    :.|..|....:      :.:.|.|..|                         |:.|...
 Frog   295 KH----SSLNDGHKVQSHKPLKDLLLVPTAGHP-------------------------RQLNEFF 330

  Fly   478 RTGRLFGGLINDIKRKAPWYISDYKDAL------SMQCVASWIFLYFACLSPIITFGGLLAEATG 536
            ..|:   |:.:||.|:.|.|..|:.|.:      ..:.:.:.||||||||.|.|.||.|..|:|.
 Frog   331 NVGK---GIFDDIARRLPVYPLDFTDGIIGNNKAIGKYITTMIFLYFACLLPSIAFGSLNDESTA 392

  Fly   537 KHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEFCLKMGWDYMTFRFWIGMWV 601
            ..:...:::|...:.|:.|..||||||.:|.:|.|:.::.::|...|.....|:..|..|.|:|.
 Frog   393 GVIDVQKTIVGQCIGGVIYSLFSGQPLVVLLTTAPLALYINVIRGICDDYNLDFKAFYAWTGLWN 457

  Fly   602 AGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVIGKNFPVNQGIYDCVCTPPI 666
            :...|:.:..:.|.|:....|.|||..|..|:..|:..|::.::.|.|.:.:.           |
 Frog   458 SCFLILYSLFNCSLLMKLFKRSTEEIIALFISITFVLDALKGIIKIFKKYYLE-----------I 511

  Fly   667 GSNASVID--YAKY----NWDS----CESYNGTLVGGDCGTPPTENVF------LMSVVLCAGTF 715
            .|:.:..|  |.|:    |:.|    ..::||::...: |:...|.:.      ::|::|..||.
 Frog   512 PSSHTYPDQEYNKHLPNLNFTSDVLLNSTFNGSVFAPN-GSSDHEEIHYGRESAVLSLMLMFGTL 575

  Fly   716 LISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAMSF-------------FDYSLGVPTQKLEVP 767
            .:...|.:||.:.:..|.||:.:||.::.|::...|.             |:|   :.|:.:.|
 Frog   576 WLGHTLYQFKKSPYLHSRVREMLSDCALPISVLTFSVVGSYFFKEIHIAKFNY---IKTESMFV- 636

  Fly   768 NELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITAVIVNRKENKLKKGCGYH 832
              |.|..|         :...|..||:...|   |.::|.|::|.|.|.:.|..||:|.||..||
 Frog   637 --LAPIGS---------LSMGPITSAMGLGF---LLSMLFFIEQNIVASLTNAPENRLVKGTAYH 687

  Fly   833 LDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGE-KPQFLGVREQRVTHILIF 896
            .||.:::::....|:.|:||..||...|..||.:|....|....|. ....:.|||.|:|.::..
 Frog   688 WDLLLVALINTGLSVFGMPWIHAAFPHSPMHVRALANVEERVEHGHIYETIVSVRETRLTSLVAN 752

  Fly   897 LTIGVSVLLTPL-LGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPAKYQPDYMFLRQVPIK 960
            :.:|:|:.|.|. |..||.|||:|:|||:.:.|:.|.|.|:|:.::.......|...::|:||.:
 Frog   753 VLVGLSLFLLPYPLQWIPKPVLYGLFLYIALTSIDGSQLFERVALLLKEQTAYPPTHYIRRVPQR 817

  Fly   961 RVHLFTMIQLACLIIL--WLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRRELKILDDIMPEMT 1023
            ::|.||.:|:..|:||  :.:.......::|||:::.||.||.               :::|::.
 Frog   818 KIHYFTGLQVLQLVILCGFGMSPLPYMKMIFPLIMIGMIPIRY---------------NLLPKII 867

  Fly  1024 KRAAADDLHKLDAEDNHH 1041
                  :...|||.|..|
 Frog   868 ------ESKYLDAMDAEH 879

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	ae	140..1016	CDD:273290	240/966 (25%)
		Band_3_cyto	167..435	CDD:284893	66/312 (21%)
		HCO3_cotransp	476..968	CDD:279322	151/528 (29%)
slc4a11	XP_031751114.1	HCO3_cotransp	334..825	CDD:395762	150/523 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265068at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1874
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950