Protein Alignment Ndae1 and slc4a5b

DIOPT Version :9

• Sequence 1: NP_723263.2
• Gene: Ndae1 / 34005
• FlyBaseID: FBgn0259111
• Length: 1190
• Species: Drosophila melanogaster
• Sequence 2: XP_021335145.1
• Gene: slc4a5b / 100006379
• ZFINID: ZDB-GENE-091112-19
• Length: 1088
• Species: Danio rerio
• Alignment Length: 1121
• Identity: 496/1121 - (44%)
• Similarity: 690/1121 - (61%)
• Gaps: 130/1121 - (11%)

  Fly    45 GHRA-------HTVYVGVHVP-----------GGRRHSQRRRKHH----HSGPGGGGGGGGGGGS 87
            |||:       .:||:||.||           ...|||..|.|||    |:.|
Zfish    12 GHRSKHNEDEEESVYIGVPVPRSYRRKRRHRKHASRHSHDRDKHHSRHEHADP------------ 64

  Fly    88 IGGSGSVGGGAGKDNV--SEKQQE-----VERPVTPPAQRVQFILGEDVDDGTHVSHPLFSEMGM 145
                        ::|.  .|.:||     |...|:|.|:|::.||.|| |:.|..   ||:||..
Zfish    65 ------------EENCDPEEAEQENELSDVNSTVSPAAERLRHILRED-DEPTPT---LFTEMDT 113

  Fly   146 LVKEGDEIEWKETARWIKFEEDVEEGGNRWSKPHVATLSLHSLFELRRLLVNGSVMLDMEAQNLE 210
            |..||.|:||||:|||:||||.|||||.|||||||:|||||||||||..|..|.::||::..:|.
Zfish   114 LQHEGGEMEWKESARWVKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGCILLDLDGYSLP 178

  Fly   211 VMADLVCDHMVSAGTLPPGVKDKVKDALLRRHRHQHEYAKKTRLPIIRSLADMRNHSSSKKKKSN 275
            .:.|.:.:..|..|.:.|.:::||...|||:||||      |:.||.|||||:...|.|.:..|.
Zfish   179 QIVDDMIEKQVQEGLIAPEIREKVSFVLLRKHRHQ------TKKPIHRSLADIGKPSPSNRSPSP 237

  Fly   276 SKHSRPAQNLSSITEDMVKSPS------NQSMARPGSGTELSEQQHKGNTHFMRKIPPGAEASNI 334
            |..:|........|||:....|      :.|..|..:...::....:....||:|||..|||||:
Zfish   238 SPSARSGSGFHRSTEDLRARQSAGLGKLHPSQCRSMNDISVTPSSDQLKNKFMKKIPRDAEASNV 302

  Fly   335 LVGEVDFLERTLSCFIRLSQAVVLGDLTEVPVPTRFVFILLGPPGSQSNFHEIGRAMATLMSDEI 399
            |:||||||::....|:||:||..||.||||||||||:|:||||.|...:::||||||||||.|::
Zfish   303 LIGEVDFLDKPFVAFVRLAQAATLGGLTEVPVPTRFLFVLLGPSGKTKSYNEIGRAMATLMVDDL 367

  Fly   400 FHEVAYRARKRDHLLSGVDEFLDAVTVLPPGEWDPTIRIEPPAAIPSQEVRKRPPELPK------ 458
            |.:|||:||.|:.|::|:|||||.|.|||||||||.||||||..:||.|:||....|.:
Zfish   368 FSDVAYKARDREDLIAGIDEFLDEVIVLPPGEWDPKIRIEPPKKLPSAEMRKSVFSLNELGQPNG 432

  Fly   459 ----EEVDEEEEEARLREENG--LSRTGRLFGGLINDIKRKAPWYISDYKDALSMQCVASWIFLY 517
                .....|:||.....|.|  |..|||..|||..||||||||:.||:.:...:|.|::.:|:|
Zfish   433 NAGGGSASAEDEEMPAPHELGEELKFTGRFCGGLWLDIKRKAPWFFSDFYEGFHIQSVSAVLFIY 497

  Fly   518 FACLSPIITFGGLLAEATGKHMAAMESLVSGFVCGMGYGFFSGQPLTILGSTGPVLVFESIIYEF 582
            ..|::..|||||||.:||..:...|||.:...:.|..:..|.||||.||.||||:|:||.::|||
Zfish   498 LGCITNAITFGGLLGDATDNYQGVMESFLGTALAGAVFCMFGGQPLIILSSTGPILIFEKLLYEF 562

  Fly   583 CLKMGWDYMTFRFWIGMWVAGICIVLTAIDASALVCYITRFTEENFATLIAFIFIYKAIENVMVI 647
            .:....|||..|.|||:.....|::|.|.|||.::.|:||||||.|::||:||||..|::.:|..
Zfish   563 SINNNIDYMEIRLWIGLHSCLQCLILVATDASYIIKYMTRFTEEGFSSLISFIFISDALKKMMST 627

  Fly   648 GKNFPVNQGI-------YDCVC-----TPPIGSNA-----SVIDYAKYNWDS----------CES 685
            ...:|::...       |.|.|     ..|:.|.:     ::.||:.:|:.:          |..
Zfish   628 FSYYPISPDFKPDLIISYRCDCQLPDQVSPLNSTSPLALENMSDYSMFNFSALDWTQISKKECLR 692

  Fly   686 YNGTLVGGDCGTPPTENVFLMSVVLCAGTFLISTVLKEFKNALFFPSIVRQYISDFSVLIAIFAM 750
            ..|:|||..|...|  ::.::|.:|..||:.::..||:||::.:||:..|..|:||:::|:|...
Zfish   693 LGGSLVGKSCKYVP--DLAMLSFILFFGTYSMTISLKKFKSSRYFPTKCRALIADFAIIISILVF 755

  Fly   751 SFFDYSLGVPTQKLEVPNELKPTLSTRGWLIPPFVEKNPWWSAIIAVFPALLGTILIFMDQQITA 815
            ...||.:.:.|.||.||.::|||...|||::.| :.:||||..:.:..||||.||||||||||||
Zfish   756 CAVDYGMALDTPKLHVPTQIKPTRPDRGWIVMP-MGRNPWWMCLASFVPALLVTILIFMDQQITA 819

  Fly   816 VIVNRKENKLKKGCGYHLDLFILSILIAICSMMGLPWFVAATVLSINHVNSLKLESECSAPGEKP 880
            |||||||||||||||||||||.:.:|:|:||.|||||:|||||:||.|::|||:|||.|||||:|
Zfish   820 VIVNRKENKLKKGCGYHLDLFWVGVLMAVCSFMGLPWYVAATVISIAHIDSLKMESESSAPGEQP 884

  Fly   881 QFLGVREQRVTHILIFLTIGVSVLLTPLLGNIPMPVLFGVFLYMGVASLKGLQFFDRILIMFMPA 945
            |||||||||:|..|:|:..||||.:.|:|..||||||:|||||||||||.|:||::||.:..|||
Zfish   885 QFLGVREQRLTGTLVFVLTGVSVFMAPILQFIPMPVLYGVFLYMGVASLHGIQFWERIKLYLMPA 949

  Fly   946 KYQPDYMFLRQVPIKRVHLFTMIQLACLIILWLIKSFSQTSILFPLMLVVMIGIRKALDLVFTRR 1010
            |:|||::|||.||::||||||::|:.||.:||::|| :..:|:||:|::.::.:||||||:|::.
Zfish   950 KHQPDFVFLRHVPLRRVHLFTLLQITCLAVLWILKS-TVAAIVFPVMILGLMVVRKALDLIFSQH 1013

  Fly  1011 ELKILDDIMPEMTKRAAADDLHKLDAEDNHHQHPPGSGAGANYNADK------SGPTTIHIPLS- 1068
            :|..||||:|:..|:...|:..|..::.:.|.           |:|:      ...:::.|||.
Zfish  1014 DLAWLDDILPDKDKKKKEDEKKKKKSKTDEHN-----------NSDEECVCAVDSSSSLKIPLEL 1067

  Fly  1069 GNKTGTKGPTVNIPQE 1084
            .|.:....|..:.|.|
Zfish  1068 LNPSSNPPPASHTPSE 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ndae1	NP_723263.2	ae	140..1016	CDD:273290	444/920 (48%)
		Band_3_cyto	167..435	CDD:284893	134/273 (49%)
		HCO3_cotransp	476..968	CDD:279322	255/518 (49%)
slc4a5b	XP_021335145.1	Band_3_cyto	108..1019	CDD:331698	444/920 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575024
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D138594at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940