Protein Alignment mEFG1 and fusA

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_417799.1
• Gene: fusA / 947847
• ECOCYCID: EG10360
• Length: 704
• Species: Escherichia coli
• Alignment Length: 715
• Identity: 320/715 - (44%)
• Similarity: 451/715 - (63%)
• Gaps: 35/715 - (4%)

  Fly    38 PIERIRNIGISAHIDSGKTTLTERILFYTG---RIAEMHEVRGKDNVGATMDSMELERQRGITIQ 99
            ||.|.||||||||||:||||.|||||||||   :|.|:|:      ..||||.||.|::|||||.
E. coli     6 PIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHD------GAATMDWMEQEQERGITIT 64

  Fly   100 SAATYTLW-------KDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQ 157
            ||||...|       :...|||||||||||||:||||::|||||||:|.|||||||.|:.||.||
E. coli    65 SAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQ 129

  Fly   158 MKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKAI-YF 221
            ..:|.||.:||:||:||:|:|..:|::|:::::..|...:||.||.|.:..|:||||:.||| :.
E. coli   130 ANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWN 194

  Fly   222 EGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDDIKAALRRTCINR 286
            :.:.|:....::||.||...:.|..|.|||..:.|.|.|.|.:|..:..||.:||.|||:..:|.
E. coli   195 DADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNN 259

  Fly   287 TFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEGQDPEKVVLNPA-RDGKD--PFV 348
            ....|..|:|.||||||.:||||:||||:|.:|..:..|..:|:|      .|| |...|  ||.
E. coli   260 EIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKD------TPAERHASDDEPFS 318

  Fly   349 GLAFKLEAGRF-GQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHSNQMEDVNEVYAGDIF 412
            .||||:....| |.||:.|.|.||:..||.:.|:....:.|..|:|::|:|:.|::.||.||||.
E. coli   319 ALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIA 383

  Fly   413 ALFGV-DCASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHF 476
            |..|: |..:|||. .:|...:.:|.:..||||:|:|::|....|::....|:.|..||||:|..
E. coli   384 AAIGLKDVTTGDTL-CDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRV 447

  Fly   477 FFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETL-VGPCEFDYLHKKQSGGS 540
            :.|.:..:|:::|||||||:|...||:||:.....:|||:||:|||: ....:.:..|.|||||.
E. coli   448 WTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQSGGR 512

  Fly   541 GQYARIIGVMEPLPPNQNTL-LEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFR 604
            |||..::..|.||.|..|.. .||:::..|..:|.:::|.|:||.:|..:.|.|:|:.:..:..|
E. coli   513 GQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIR 577

  Fly   605 LQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGII 669
            |..|.:|.||||||||.|||..|.||.|:.....:|||||.|||..|||..|.|:|.||:|.|::
E. coli   578 LHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGML 642

  Fly   670 TGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQDQIVRQYQESQG 734
            .|.|.......::|||||::|||||.:|||.|:|:..:|||:.:|.....:|...::    |::|
E. coli   643 KGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVI----EARG 703

  Fly   735  734
            E. coli   704  703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	318/710 (45%)
fusA	NP_417799.1	FusA	1..704	CDD:440248	320/715 (45%)