Protein Alignment mEFG1 and RIA1

DIOPT Version :9

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_014236.1
• Gene: RIA1 / 855558
• SGDID: S000005107
• Length: 1110
• Species: Saccharomyces cerevisiae
• Alignment Length: 1110
• Identity: 216/1110 - (19%)
• Similarity: 381/1110 - (34%)
• Gaps: 424/1110 - (38%)

  Fly    42 IRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTL 106
            ||||.|.||:|.|||:|::.:|...|.|::  .:.||...   :|:...|:.||||::|:|....
Yeast    19 IRNICIVAHVDHGKTSLSDSLLASNGIISQ--RLAGKIRF---LDARPDEQLRGITMESSAISLY 78

  Fly   107 WK--------------DTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVNRQ 157
            ::              :..:|:||:|||:||:.||..|.|:.||||:::..|.||.|||:||.||
Yeast    79 FRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVVEGVCSQTVTVLRQ 143

  Fly   158 MKRYNVPCLAFINKLDRL-------GSNPY----RVLSQMRS---------------------KM 190
            .....:..:..:||:|||       ....|    :|:.|:.|                     :.
Yeast   144 CWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANERQLDDLFWREQLEK 208

  Fly   191 NHNAAFIQLPIGVESNCKGI--------------VD----LVREKAIYFE--------------- 222
            |.||.:|      |.:..||              :|    .:.:.|.::|
Yeast   209 NENAEYI------EKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAKRENLQKVLW 267

  Fly   223 GEHGMDIRLDEI--PQDMRVESLE---------------------RRQELIEHLSNADETLGELF 264
            |:..||.:..:|  .:.::..||:                     |..|::|.::   :||....
Yeast   268 GDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIA---KTLNIKL 329

  Fly   265 LEEKPFTEDD-------------IKAALRRTCINRTFTP----------VLVG------------ 294
            |.....::||             :..|:..|.|.:..:|          :||.
Yeast   330 LARDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILVSESDTAAMDPRLL 394

  Fly   295 TALK---NKG-----VQPLLDAVLDYLP----------------------------NPGEVENLG 323
            .|:|   .:|     |..:|....:.||                            :.|.|||:.
Yeast   395 KAMKTCDKEGPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAREEALNAAKHAGMVENMA 459

  Fly   324 FIE------------KEGQD----PEK----------------VVLNPA--------------RD 342
            .::            |..:|    ||.                ||..|:              .|
Yeast   460 MMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSALDLEFEYEGEDDSD 524

  Fly   343 GKDPFVGLAF----------------------KLEAGR-------------FGQ-----LTYLRC 367
            .:|.| ||.|                      .||:.:             |.:     :.:.|.
Yeast   525 SQDNF-GLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIFDEKEECLVAFARI 588

  Fly   368 YQGVLRKGDNI------FNAR-TNKKVRIARLVRLH---SNQMEDVNEVYAGDIFALFGV--DCA 420
            |.|.||.|..|      ::.: ..:.:..|.:..|:   ..::..::...:|:|..:.|:  ...
Yeast   589 YSGTLRVGQEISVLGPKYDPKCPEEHIETAIITHLYLFMGKELVPLDVCPSGNIVGIRGLAGKVL 653

  Fly   421 SGDTFTTNPKNNLSMESI-FVPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKE 484
            ...|........:::..: |...|:|.:|::|.|..:.....:.:....:.||..|.:.:| ..|
Yeast   654 KSGTLIEKGVQGVNLAGVNFHFTPIVRVAVEPANPVEMSKLVRGLKLLDQADPCVHTYVEN-TGE 717

  Fly   485 TLVSGMGELHLEIYAQRM-EREYGCPVTLGKPKVAFRETLVGPCEF------------------- 529
            .::...||||||...:.: ||..|..:|..:|.:.:|||.:...:.
Yeast   718 HILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSASDMNPPQNSQLGRGVHELLLSQ 782

  Fly   530 ---------------DYLHKKQSGGSGQYARIIGVMEPLPP-------NQNTLLEFVDETV---- 568
                           |:|.:.|:............|:|:..       ::.:||...:|.:
Yeast   783 YKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSMDPVIESTGSSFLDKKSLLVAFEEVINQEE 847

  Fly   569 --------------------------------------GTNVPKQFVPGVEKGYREMAEKGML-- 593
                                                  ||....::...::.|::....:|.|
Yeast   848 KSRELLSGFKVKLAGFGPSRVGCNILLSQDNLLGSLFEGTPAAFEYSDSIKNGFQLAVSEGPLAN 912

  Fly   594 -----------SGHKLSGIRFR-LQDGGH--HIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIM 644
                       |.||:|..... ::|..:  ||||.|. ..:.:...||.|.|.:.|.:|:..|.
Yeast   913 EPVQGMCVLVESVHKMSQDEIESIEDPRYQQHIVDLSG-RLITSTRDAIHEAFLDWSPRIMWAIY 976

  Fly   645 LVEVTAPEEFQGAVMGHLSKRHGIITGTEGTEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEF 707
            ..::....:..|.|...:.:|||.|...|..||  :|.:.|.||:.:.||.:.::|..|.|..:.
Yeast   977 SCDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSEDIRKRTSGAAQP 1041

  Fly   708 TMEYSRYSPC-----------------LPDVQDQ--IVRQYQES----QGL---------AQPDK 740
            .:.:|.:. |                 |.|..|:  |.|::..:    :||         |:..:
Yeast  1042 QLVFSGFE-CIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRRKGLFIEEKVVENAEKQR 1105

  Fly   741 KKKKN 745
            ..|||
Yeast  1106 TLKKN 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	EF-G	44..316	CDD:206673	95/444 (21%)
		PRK12740	48..727	CDD:237186	204/1071 (19%)
		mtEFG1_II_like	347..427	CDD:293908	20/131 (15%)
		EFG_III	441..516	CDD:293919	20/75 (27%)
		EFG_mtEFG1_IV	519..636	CDD:238715	30/215 (14%)
		mtEFG1_C	641..718	CDD:239764	21/95 (22%)
RIA1	NP_014236.1	FusA	1..1091	CDD:357662	210/1089 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810