Protein Alignment mEFG1 and MEF2

DIOPT Version :9

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_012433.1
• Gene: MEF2 / 853342
• SGDID: S000003638
• Length: 819
• Species: Saccharomyces cerevisiae
• Alignment Length: 805
• Identity: 230/805 - (28%)
• Similarity: 381/805 - (47%)
• Gaps: 151/805 - (18%)

  Fly    27 YSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSMELE 91
            |.|.|:    .|:.::|||||.||||:||||.|||:|:|.|....:.:|...|.:   .|.:|.|
Yeast    30 YLSTAR----SPLSKVRNIGIIAHIDAGKTTTTERMLYYAGISKHIGDVDTGDTI---TDFLEQE 87

  Fly    92 RQRGITIQSAATYTLWKDT-NINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLTVN 155
            |.|||||||||....|::| .||:||||||:|||.||.|||:|:|..|::|.||.||::||..|.
Yeast    88 RSRGITIQSAAISFPWRNTFAINLIDTPGHIDFTFEVIRALKVIDSCVVILDAVAGVEAQTEKVW 152

  Fly   156 RQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAA----------FIQLPIGVESNCKGI 210
            :|.|  :.|.:.||||:||:|::....::.:.:|......          :.:.|...:...:|:
Yeast   153 KQSK--SKPKICFINKMDRMGASFNHTVNDLINKFMRGTTTKPVLVNIPYYRKQPTSNDYVFQGV 215

  Fly   211 VDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLER-RQELIEHLSNADETLGELFLEEKPFTEDD 274
            :|:|..|.:.:..|:..:|.:||: ....:|...| |:.:||.|:..||.|.:.||||   .|.|
Yeast   216 IDVVNGKRLTWNPENPDEIIVDEL-DGTSLEQCNRCRESMIETLTEYDEDLVQHFLEE---AEGD 276

  Fly   275 --------IKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKE--- 328
                    :.|::|:..:.....|||.|.:.||.||||||||:::|||:|.|.|.....:|.
Yeast   277 YSKVSAQFLNASIRKLTMKNMIVPVLCGASFKNIGVQPLLDAIVNYLPSPIEAELPELNDKTVPM 341

  Fly   329 GQDPEKVVLNPARDGKDPFVGLAFKLEAGRF-GQLTYLRCYQGVLRKGDNIFNARTNKKVRIARL 392
            ..||:...|  ..:.|:..:.||||:..... |:..::|.|.|.|..|:.::|:.|.:|.::.:|
Yeast   342 KYDPKVGCL--VNNNKNLCIALAFKVITDPIRGKQIFIRIYSGTLNSGNTVYNSTTGEKFKLGKL 404

  Fly   393 VRLHSNQMEDVNEVYAGDIFALFGV----DCASGDTFTTNPKN-------------NLSMESIFV 440
            :..|:...:.||.:.||.|..|.|.    :.::|||..|:...             .|.:.|||:
Yeast   405 LIPHAGTSQPVNILTAGQIGLLTGSTVENNISTGDTLITHSSKKDGLKSLDKKKELTLKINSIFI 469

  Fly   441 PEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMERE 505
            |.||..::|:|....::.:..:|:.....|||:.....:::..:|:::|||||||||...|:..:
Yeast   470 PPPVFGVSIEPRTLSNKKSMEEALNTLITEDPSLSISQNDETGQTVLNGMGELHLEIAKDRLVND 534

  Fly   506 YGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARIIGVME-----------PLPPNQNT 559
            ....|..|:..|:::||:......: .::...|    |...:.::.           ||..|:|.
Yeast   535 LKADVEFGQLMVSYKETINSETNIE-TYESDDG----YRFSLSLLPNSDALPNCLAYPLGVNENF 594

  Fly   560 LL-------------EFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQ----- 606
            |:             :...|::..::....:.|:::|       |.::...|.....::.
Yeast   595 LIMEKNGNWDKEWKYQVSFESILNSIIASCIVGLQRG-------GKIANFPLYACSIKINSDWSV 652

  Fly   607 ----DGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLS-KRH 666
                :....|:..:......|.:....|     .:.:|||||.:::|.|:...|.|:..|: .|.
Yeast   653 PPDIETPQEILKITRNLIFKALNDLKPE-----KYNLLEPIMNLDLTIPQSDVGTVLQDLTGARK 712

  Fly   667 GIITGTE-----GTEGWFT---------------------------------------VYAEVPL 687
            ..|...|     ...|..|                                       :.|:|||
Yeast   713 AQILSIEDESSVSNSGASTCNSPENSNRIYIPSDAVTTLHATKDKKNTQETSSNVKKIIKAKVPL 777

  Fly   688 NDMFGYAGELRSSTQGKGEFTMEYS 712
            .::..|..:|||.:||:|||.:|||
Yeast   778 REITTYTNKLRSLSQGRGEFNIEYS 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	EF-G	44..316	CDD:206673	116/291 (40%)
		PRK12740	48..727	CDD:237186	221/784 (28%)
		mtEFG1_II_like	347..427	CDD:293908	25/84 (30%)
		EFG_III	441..516	CDD:293919	22/74 (30%)
		EFG_mtEFG1_IV	519..636	CDD:238715	17/149 (11%)
		mtEFG1_C	641..718	CDD:239764	30/117 (26%)
MEF2	NP_012433.1	FusA	37..817	CDD:223556	227/794 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810