Protein Alignment mEFG1 and EFT2

DIOPT Version :9

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_010673.1
• Gene: EFT2 / 851993
• SGDID: S000002793
• Length: 842
• Species: Saccharomyces cerevisiae
• Alignment Length: 862
• Identity: 212/862 - (24%)
• Similarity: 343/862 - (39%)
• Gaps: 210/862 - (24%)

  Fly    39 IERIRNIGISAHIDSGKTTLTERILFYTGRI--AEMHEVRGKDNVGATMDSMELERQRGITIQSA 101
            :..:||:.:.||:|.||:|||:.::...|.|  |:..|.|       ..|:.:.|::|||||:|.
Yeast    16 VTNVRNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEAR-------FTDTRKDEQERGITIKST 73

  Fly   102 A--TYTLWKDTN--------------INIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQ 150
            |  .|:...|.:              ||:||:||||||:.||..||||.|||::|:..:.||..|
Yeast    74 AISLYSEMSDEDVKEIKQKTDGNSFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQ 138

  Fly   151 TLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLV- 214
            |.||.||.....:..:..|||:||      .:|....||.:....|.:....|........|.|
Yeast   139 TETVLRQALGERIKPVVVINKVDR------ALLELQVSKEDLYQTFARTVESVNVIVSTYADEVL 197

  Fly   215 --------REKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFL--EEKP 269
                    |....:..|.||....:.:.      .:...::..::.....|...|:.|.  :.|.
Yeast   198 GDVQVYPARGTVAFGSGLHGWAFTIRQF------ATRYAKKFGVDKAKMMDRLWGDSFFNPKTKK 256

  Fly   270 FTEDDIKA---ALRRTC-------INRTFT----------PVLV---------------GTALKN 299
            :|..|..|   .|.|..       |.|.||          |||:               |.||..
Yeast   257 WTNKDTDAEGKPLERAFNMFILDPIFRLFTAIMNFKKDEIPVLLEKLEIVLKGDEKDLEGKALLK 321

  Fly   300 ---KGVQPLLDAVLD----YLPNPGEVENLGFIEKEGQDPEKVVLNPARDGK-------DPFVGL 350
               :...|..||:|:    :||:|        :..:....|::...||.|..       ||...|
Yeast   322 VVMRKFLPAADALLEMIVLHLPSP--------VTAQAYRAEQLYEGPADDANCIAIKNCDPKADL 378

  Fly   351 AFKL-------EAGRFGQLTYLRCYQGVLRKGDNIF----NARTNKK-----VRIARLVRLHSNQ 399
            ...:       :.|||  ..:.|.:.|.::.|..:.    |....||     ..|.|:|.:....
Yeast   379 MLYVSKMVPTSDKGRF--YAFGRVFAGTVKSGQKVRIQGPNYVPGKKDDLFIKAIQRVVLMMGRF 441

  Fly   400 MEDVNEVYAGDIFALFGVD---CASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRDNFS 461
            :|.:::..||:|..|.|:|   ..:|...|:...:|:.:.. |...|||.:|::..|..|.....
Yeast   442 VEPIDDCPAGNIIGLVGIDQFLLKTGTLTTSETAHNMKVMK-FSVSPVVQVAVEVKNANDLPKLV 505

  Fly   462 KAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREY-GCPVTLGKPKVAFRETLVG 525
            :.:.|.:|.||.. ..:.::..|.:|:|.|||||||..|.:|.:: |.|:.:..|.||:|||:
Yeast   506 EGLKRLSKSDPCV-LTYMSESGEHIVAGTGELHLEICLQDLEHDHAGVPLKISPPVVAYRETV-- 567

  Fly   526 PCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNTLLE---------------------------- 562
              |.:......|....::.||....||:....:..:|
Yeast   568 --ESESSQTALSKSPNKHNRIYLKAEPIDEEVSLAIENGIINPRDDFKARARIMADDYGWDVTDA 630

  Fly   563 ---------------FVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQD----- 607
                           .:|:|.......:....|...::...::|.:.|.::..:|..:.|
Yeast   631 RKIWCFGPDGNGPNLVIDQTKAVQYLHEIKDSVVAAFQWATKEGPIFGEEMRSVRVNILDVTLHA 695

  Fly   608 -----GGHHIVDSSELA----FMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLS 663
                 ||..|:.:...|    |:||            ..:|.||:.|||:..||:..|.:...|:
Yeast   696 DAIHRGGGQIIPTMRRATYAGFLLA------------DPKIQEPVFLVEIQCPEQAVGGIYSVLN 748

  Fly   664 KRHGIITGTEGTEG--WFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCLPDVQD--- 723
            |:.|.:...|...|  .|||.|.:|:|:.||:.||||.:|.|:....|.:..:|....|..|
Yeast   749 KKRGQVVSEEQRPGTPLFTVKAYLPVNESFGFTGELRQATGGQAFPQMVFDHWSTLGSDPLDPTS 813

  Fly   724 ---QIVRQYQESQGLAQ 737
               :||...::..|:.:
Yeast   814 KAGEIVLAARKRHGMKE 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	EF-G	44..316	CDD:206673	94/342 (27%)
		PRK12740	48..727	CDD:237186	208/841 (25%)
		mtEFG1_II_like	347..427	CDD:293908	21/98 (21%)
		EFG_III	441..516	CDD:293919	24/75 (32%)
		EFG_mtEFG1_IV	519..636	CDD:238715	24/173 (14%)
		mtEFG1_C	641..718	CDD:239764	29/78 (37%)
EFT2	NP_010673.1	PTZ00416	1..842	CDD:240409	212/862 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810