DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mEFG1 and AT1G45332

DIOPT Version :9

Sequence 1:	NP_609105.1	Gene:	mEFG1 / 34004	FlyBaseID:	FBgn0263133	Length:	745	Species:	Drosophila melanogaster
Sequence 2:	NP_175135.1	Gene:	AT1G45332 / 841097	AraportID:	AT1G45332	Length:	754	Species:	Arabidopsis thaliana

Alignment Length:	734	Identity:	399/734 - (54%)
Similarity:	522/734 - (71%)	Gaps:	19/734 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLTGNNTLRLRALKSLGKAGYSSHAKFSEHKP-----IERIRNIGISAHIDSGKTTLTERILFYT 66
            ||||:..| :|..    .||.::.....|.:|     ::::|||||||||||||||||||:||||
plant    30 LLTGDFQL-IRHF----SAGTAARVAKDEKEPWWKESMDKLRNIGISAHIDSGKTTLTERVLFYT 89

  Fly    67 GRIAEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERAL 131
            |||.|:|||||:|.|||.||||:|||::||||||||||..|||..:||||||||||||:||||||
plant    90 GRIHEIHEVRGRDGVGAKMDSMDLEREKGITIQSAATYCTWKDYKVNIIDTPGHVDFTIEVERAL 154

  Fly   132 RVLDGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAF 196
            ||||||:||||:|||||||::||:|||:||.||.:||||||||:|::|::||:|.|:|:.|::|.
plant   155 RVLDGAILVLCSVGGVQSQSITVDRQMRRYEVPRVAFINKLDRMGADPWKVLNQARAKLRHHSAA 219

  Fly   197 IQLPIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLG 261
            :|:|||:|.|.:|::||:..||.:|.|..|.::...:||.||.....|:|:||||.:|..|:.|.
plant   220 VQVPIGLEENFQGLIDLIHVKAYFFHGSSGENVVAGDIPADMEGLVAEKRRELIETVSEVDDVLA 284

  Fly   262 ELFLEEKPFTEDDIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIE 326
            |.||.::|.:..:::.|:||..|.:||.||.:|:|.||||||||||.|:.:||:|.||.|  :..
plant   285 EKFLNDEPVSASELEEAIRRATIAQTFVPVFMGSAFKNKGVQPLLDGVVSFLPSPNEVNN--YAL 347

  Fly   327 KEGQDPEKVVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIAR 391
            .:..:.|:|.|..:.||  |.|.||||||.||||||||||.|:||::|||.|.|..|.|::::.|
plant   348 DQNNNEERVTLTGSPDG--PLVALAFKLEEGRFGQLTYLRVYEGVIKKGDFIINVNTGKRIKVPR 410

  Fly   392 LVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKD 456
            |||:|||.|||:.|.:||.|.|:||::||||||| |:.....:|.|:.|||||:|:|::|.:...
plant   411 LVRMHSNDMEDIQEAHAGQIVAVFGIECASGDTF-TDGSVKYTMTSMNVPEPVMSLAVQPVSKDS 474

  Fly   457 RDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRE 521
            ...||||:.||.||||||....|.:..:|::||||||||:||.:||.|||....|:|||:|.|||
plant   475 GGQFSKALNRFQKEDPTFRVGLDPESGQTIISGMGELHLDIYVERMRREYKVDATVGKPRVNFRE 539

  Fly   522 TLVGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYRE 586
            |:....||||||||||||:|||.|:.|.:|||||......||.:..||..:|..|:|.:|||::|
plant   540 TITQRAEFDYLHKKQSGGAGQYGRVTGYVEPLPPGSKEKFEFENMIVGQAIPSGFIPAIEKGFKE 604

  Fly   587 MAEKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAP 651
            .|..|.|.||.:..:|..|.||..|.||||||||.:||..|.:..:......||||:||||:..|
plant   605 AANSGSLIGHPVENLRIVLTDGASHAVDSSELAFKMAAIYAFRLCYTAARPVILEPVMLVELKVP 669

  Fly   652 EEFQGAVMGHLSKRHGIITGT--EGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRY 714
            .||||.|.|.::||.|||.|.  ||.:...|  |.||||:||||:..|||.|||||||||||..:
plant   670 TEFQGTVAGDINKRKGIIVGNDQEGDDSVIT--ANVPLNNMFGYSTSLRSMTQGKGEFTMEYKEH 732

  Fly   715 SPCLPDVQDQIVRQYQESQ 733
            |....:||.|:|..|..|:
plant   733 SAVSNEVQAQLVNAYSASK 751

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	EF-G	44..316	CDD:206673	170/271 (63%)
		PRK12740	48..727	CDD:237186	381/680 (56%)
		mtEFG1_II_like	347..427	CDD:293908	51/79 (65%)
		EFG_III	441..516	CDD:293919	39/74 (53%)
		EFG_mtEFG1_IV	519..636	CDD:238715	58/116 (50%)
		mtEFG1_C	641..718	CDD:239764	46/78 (59%)
AT1G45332	NP_175135.1	PRK12740	71..744	CDD:237186	381/679 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	362	1.000	Domainoid score	I190
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6449
Inparanoid	1	1.050	777	1.000	Inparanoid score	I96
OMA	1	1.010	-	-		QHG62898
OrthoDB	1	1.010	-	-		D637899at2759
OrthoFinder	1	1.000	-	-		FOG0003241
OrthoInspector	1	1.000	-	-		otm2950
orthoMCL	1	0.900	-	-		OOG6_100770
Panther	1	1.100	-	-	LDO	PTHR43636
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2192
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840