Protein Alignment mEFG1 and gfm1

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_001073463.1
• Gene: gfm1 / 561840
• ZFINID: ZDB-GENE-061013-79
• Length: 745
• Species: Danio rerio
• Alignment Length: 742
• Identity: 478/742 - (64%)
• Similarity: 588/742 - (79%)
• Gaps: 12/742 - (1%)

  Fly    16 LRALKSLGKAGYSSHAKFSE-----------HKPIERIRNIGISAHIDSGKTTLTERILFYTGRI 69
            |||..||.:.....|:...:           ..|.||||||||||||||||||||||:|:|||||
Zfish     4 LRAASSLARLHRPGHSTLQQVLISCRSCSNGITPNERIRNIGISAHIDSGKTTLTERVLYYTGRI 68

  Fly    70 AEMHEVRGKDNVGATMDSMELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVL 134
            ||||||||||.|||.|||||||||||||||||||||:||:.||||||||||||||:||||:||||
Zfish    69 AEMHEVRGKDGVGAIMDSMELERQRGITIQSAATYTMWKNHNINIIDTPGHVDFTIEVERSLRVL 133

  Fly   135 DGAVLVLCAVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQL 199
            ||||||||||||||.||:|||||||||:||.|.|||||||||:||.|.|.|:|:|:|.||||:.:
Zfish   134 DGAVLVLCAVGGVQCQTVTVNRQMKRYSVPFLTFINKLDRLGANPNRALQQLRTKLNQNAAFVNI 198

  Fly   200 PIGVESNCKGIVDLVREKAIYFEGEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELF 264
            |||:|.|.:||:||:.|::|.|:|..|..:|.::||.:||.|:.:|||||:|.::||||||||:|
Zfish   199 PIGLEGNLRGIIDLIEERSIVFDGPFGESVRYEDIPPEMRSEAADRRQELVECVANADETLGEMF 263

  Fly   265 LEEKPFTEDDIKAALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGEVENLGFIEKEG 329
            |||:..|..|:|||:||..:.|:|:|||||:|||||||||||||||:|||||.||:|...:.:||
Zfish   264 LEERVPTVLDLKAAVRRATVKRSFSPVLVGSALKNKGVQPLLDAVLEYLPNPTEVQNYAILNEEG 328

  Fly   330 Q-DPEKVVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLV 393
            : :..|::::..||...|||||||||||||||||||:|.|||.|||.|.|.|:||.::||:.|||
Zfish   329 ESEGSKILMDSTRDDTQPFVGLAFKLEAGRFGQLTYVRVYQGCLRKTDYIHNSRTGRRVRVQRLV 393

  Fly   394 RLHSNQMEDVNEVYAGDIFALFGVDCASGDTFTTNPKNNLSMESIFVPEPVVSMAIKPNNTKDRD 458
            |||::|||||...|||||.||||:|||||||||.....|||||||.|||||:||||:|:|..|.|
Zfish   394 RLHADQMEDVEVAYAGDICALFGIDCASGDTFTARNNANLSMESIHVPEPVISMAIRPSNKNDTD 458

  Fly   459 NFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEIYAQRMEREYGCPVTLGKPKVAFRETL 523
            ..||.|:|||:|||||...||.:.|||::|||||||||||:|||||||.||..:|||||||||||
Zfish   459 KLSKGISRFTREDPTFRVHFDTESKETIISGMGELHLEIYSQRMEREYSCPCVMGKPKVAFRETL 523

  Fly   524 VGPCEFDYLHKKQSGGSGQYARIIGVMEPLPPNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMA 588
            .....|:|.|||||||||||.::|||:|||.....|.:||.|||||||:||||||.||||:|:..
Zfish   524 TSAVPFEYTHKKQSGGSGQYGKVIGVLEPLDSENYTKVEFSDETVGTNIPKQFVPAVEKGFRDAC 588

  Fly   589 EKGMLSGHKLSGIRFRLQDGGHHIVDSSELAFMLAAHGAIKEVFQNGSWQILEPIMLVEVTAPEE 653
            |||.|.|||:||:||.|:||.||:|||:|::|:.|..||:|:..:..:..||||:|.||:.||.|
Zfish   589 EKGPLIGHKISGVRFVLEDGAHHMVDSNEISFIRAGEGAVKQALEKATVVILEPVMSVEIVAPNE 653

  Fly   654 FQGAVMGHLSKRHGIITGTEGTEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPCL 718
            |||||:..:::|||:|:|.:|.:|:||:||::|||||||||.||||.|:||||:|||||||.||.
Zfish   654 FQGAVIAGVNRRHGVISGQDGADGYFTLYADIPLNDMFGYATELRSCTEGKGEYTMEYSRYQPCA 718

  Fly   719 PDVQDQIVRQYQESQGLAQPDKKKKKN 745
            ..||:.:|.::.|:.|.....|.|.||
Zfish   719 ASVQEDLVNKHLEATGQLPAKKSKWKN 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	466/693 (67%)
gfm1	NP_001073463.1	FusA	36..729	CDD:440248	466/692 (67%)