Protein Alignment mEFG1 and mRRF2

DIOPT Version :10

• Sequence 1: NP_609105.1
• Gene: mEFG1 / 34004
• FlyBaseID: FBgn0263133
• Length: 745
• Species: Drosophila melanogaster
• Sequence 2: NP_732771.2
• Gene: mRRF2 / 42670
• FlyBaseID: FBgn0051159
• Length: 740
• Species: Drosophila melanogaster
• Alignment Length: 780
• Identity: 224/780 - (28%)
• Similarity: 374/780 - (47%)
• Gaps: 134/780 - (17%)

  Fly    24 KAGYSSHAKFSEHKPIERIRNIGISAHIDSGKTTLTERILFYTGRIAEMHEVRGKDNVGATMDSM 88
            |..|||           :||||||.||||:||||.|||:|||.|:...:.||...:.|   .|.:
  Fly    26 KRSYSS-----------KIRNIGILAHIDAGKTTTTERMLFYAGKTRALGEVHRGNTV---TDYL 76

  Fly    89 ELERQRGITIQSAATYTLWKDTNINIIDTPGHVDFTVEVERALRVLDGAVLVLCAVGGVQSQTLT 153
            ..||:|||||.|:|....|.|..||::|||||:|||:|||::|..:||.|:||....||::||:|
  Fly    77 TQERERGITICSSAVTFSWNDHRINLLDTPGHIDFTMEVEQSLYAVDGVVVVLDGTAGVEAQTVT 141

  Fly   154 VNRQMKRYNVPCLAFINKLDRLGSNPYRVLSQMRSKMNHNAAFIQLPIGVESNCKGIVDLVREKA 218
            |..|..::.:|.|.|:||:||..::..:.:|.::.|:......:|.|:..|.....|.|::..:.
  Fly   142 VWSQADKHKLPRLIFVNKMDRPDADFEKCVSDLKDKLETQPVCLQYPVKNEDGVLAINDVITLER 206

  Fly   219 IYFE----GEHGMDIRLDEIPQDMRVESLERRQELIEHLSNADETLGELFLEEKPFTEDD---IK 276
            :.::    |....:::| |...|:|:.. |:|.|||:.||..|:.|.::.:..:.|...|   |:
  Fly   207 LSWQQKDLGRSYRNVKL-EPSDDLRLLQ-EKRNELIDQLSGLDDELADVVISTESFDNVDNALIE 269

  Fly   277 AALRRTCINRTFTPVLVGTALKNKGVQPLLDAVLDYLPNPGE---------VENLGFIEKEGQDP 332
            .||||....:...|||:|:|.||.|:|.|:|||..|||.|.|         .|..|.:.|...|.
  Fly   270 RALRRATTQQKVVPVLLGSAYKNVGIQRLMDAVNAYLPAPEERNQIYDCFGTEVAGKVFKIVHDK 334

  Fly   333 EKVVLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNARTNKKVRIARLVRLHS 397
            ::                         |.||.:|..:|.:::|..:.:||...:| :::|....:
  Fly   335 QR-------------------------GPLTLVRILRGEIKRGMRLISARGQAEV-VSKLYEPLA 373

  Fly   398 NQMEDVNEVYAGDIFALFGV-DCASGDTFTTNP----------KNNL--------------SMES 437
            ::..:|:.|.:||:....|: ...:||..|::.          |.:|              ..:.
  Fly   374 DEYREVSAVQSGDVVICAGLKSTVTGDLLTSSQSALKNAQKRYKQSLGNTAAKVEEDDELDESDE 438

  Fly   438 IF-----VPEPVVSMAIKPNNTKDRDNFSKAIARFTKEDPTFHFFFDNDVKETLVSGMGELHLEI 497
            :|     :|:.|...:|:|.:...:....:|:.:..:|||:....:|:...:|::.||||||::|
  Fly   439 LFAIDPQIPDAVYFCSIEPPSVSSQTAMEQALKQLQREDPSLRVSYDSVTGQTVLGGMGELHMDI 503

  Fly   498 YAQRMEREYGCPVTLGKPKVAFRETLVGPCEFDYLHKKQSGGSGQYARI----------IGVMEP 552
            ...|:..||...|.||..::|::||:..|.......:|:..||.|...|          :..::.
  Fly   504 IKSRILSEYKIDVDLGPLQIAYKETIEAPALTTLSVEKEIAGSKQSVSITLEVVKNQAELFSLDK 568

  Fly   553 LP---PNQNTLLEFVDETVGTNVPKQFVPGVEKGYREMAEKGMLSGHKLSGIRFRLQDG--GHHI 612
            .|   ||.|||            ..:.:..:.||.....|:|...|.::...:.||.:.  |...
  Fly   569 SPDNLPNLNTL------------RPRILQVLRKGSISALERGPRVGGQVVETQIRLHNATIGRGT 621

  Fly   613 VDSSELAFMLA-AHGAIKEVFQNGSWQILEPIMLVEVTAPEEFQGAVMGHLSKRHGIITGT--EG 674
            .||    |::| |...::::......::|||||.:::.||.|....:|..||:|..:|...  :|
  Fly   622 ADS----FVMATAAQCVQKLLSTSGTRLLEPIMALQIVAPSERISGIMADLSRRRALINDVLPKG 682

  Fly   675 TEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFTMEYSRYSPC----LPDVQDQIVRQYQESQGL 735
            ..... :....||.::.||:..||:.:.|....||:     ||    :..|.:.:..  :.:|||
  Fly   683 ERNKM-ILVNAPLAELSGYSSALRTISSGTASMTMQ-----PCGFSSMNSVDESLAE--RRAQGL 739

  Fly   736  735
              Fly   740  739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mEFG1	NP_609105.1	FusA	38..731	CDD:440248	217/760 (29%)
mRRF2	NP_732771.2	FusA	30..734	CDD:440248	219/769 (28%)